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Drugs reference index «Chlordiazepoxide»


Brand names: Librium

Why is Chlordiazepoxide prescribed?

Librium is used in the treatment of anxiety disorders. It is also prescribed for short-term relief of the symptoms of anxiety, symptoms of withdrawal in acute alcoholism, and anxiety and apprehension before surgery. It belongs to a class of drugs known as benzodiazepines.

Most important fact about Chlordiazepoxide

Librium is habit-forming and you can become dependent on it. You could experience withdrawal symptoms if you stop taking it abruptly (see "Librium side effects"). You should not discontinue the drug or change your dose without your doctor's approval.

How should you take Chlordiazepoxide?

Take Librium exactly as prescribed.

--If you miss a dose...

Take it as soon as you remember if it is within an hour or so of your scheduled time. If you do not remember until later, skip the dose you missed and go back to your regular schedule. Do not take 2 doses at once.

--Storage instructions...

Store away from heat, light, and moisture.

Chlordiazepoxide side effects

Side effects cannot be anticipated. If any develop or change in intensity, inform your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking Librium.

  • Side effects may include:Confusion, constipation, drowsiness, fainting, increased or decreased sex drive, liver problems, lack of muscle coordination, minor menstrual irregularities, nausea, skin rash or eruptions, swelling due to fluid retention, yellow eyes and skin
  • Side effects due to rapid decrease or abrupt withdrawal from Librium may include:Abdominal and muscle cramps, convulsions, exaggerated feeling of depression, sleeplessness, sweating, tremors, vomiting

Why should Chlordiazepoxide not be prescribed?

If you are sensitive to or have ever had an allergic reaction to Librium or similar tranquilizers, you should not take Chlordiazepoxide.

Anxiety or tension related to everyday stress usually does not require treatment with Librium. Discuss your symptoms thoroughly with your doctor.

Special warnings about Chlordiazepoxide

Librium may cause you to become drowsy or less alert; therefore, you should not drive or operate dangerous machinery or participate in any hazardous activity that requires full mental alertness until you know how you react to Librium.

If you are severely depressed or have suffered from severe depression, consult with your doctor before taking Librium.

This drug may cause children to become less alert.

If you have a hyperactive, aggressive child taking Librium, inform your doctor if you notice contrary reactions such as excitement, stimulation, or acute rage.

Consult with your doctor before taking Librium if you are being treated for porphyria (a rare metabolic disorder) or kidney or liver disease.

Possible food and drug interactions when taking Chlordiazepoxide

Librium is a central nervous system depressant and may intensify the effects of alcohol or have an additive effect. Do not drink alcohol while taking Librium.

If Librium is taken with certain other drugs, the effects of either can be increased, decreased, or altered. It is especially important to check with your doctor before combining Librium with the following:Antacids such as Maalox and MylantaAntidepressant drugs known as MAO inhibitors, including Nardil and ParnateAntipsychotic medications such as chlorpromazine and trifluoperazineBarbiturates such as phenobarbitalBlood-thinning drugs such as CoumadinCimetidine (Tagamet)Disulfiram (Antabuse)Levodopa (Larodopa)Narcotic pain relievers such as Demerol and PercocetOral contraceptives

Special information if you are pregnant or breastfeeding

Do not take Librium if you are pregnant or planning to become pregnant. There may be an increased risk of birth defects. This drug may appear in breast milk and could affect a nursing infant. If the medication is essential to your health, your doctor may advise you to discontinue breastfeeding until your treatment with the drug is finished.

Recommended dosage for Chlordiazepoxide


Mild or Moderate Anxiety

The usual dose is 5 or 10 milligrams, 3 or 4 times a day.

Severe Anxiety

The usual dose is 20 to 25 milligrams, 3 or 4 times a day.

Apprehension and Anxiety before Surgery

On days preceding surgery, the usual dose is 5 to 10 milligrams, 3 or 4 times a day.

Withdrawal Symptoms of Acute Alcoholism

The usual starting oral dose is 50 to 100 milligrams; the doctor will repeat this dose, up to a maximum of 300 milligrams per day, until agitation is controlled. The dose will then be reduced as much as possible.


The usual dose for children 6 years of age and older is 5 milligrams, 2 to 4 times per day. Some children may need to take 10 milligrams, 2 or 3 times per day. The drug is not recommended for children under 6.


Your doctor will limit the dose to the smallest effective amount in order to avoid oversedation or lack of coordination. The usual dose is 5 milligrams, 2 to 4 times per day.


Any medication taken in excess can cause symptoms of overdose. If you suspect an overdose, seek medical attention immediately.

  • The symptoms of Librium overdose may include:Coma, confusion, sleepiness, slow reflexes
  • Chlordiazepoxide MedFacts Consumer Leaflet (Wolters Kluwer)
  • Chlordiazepoxide Prescribing Information (FDA)
  • Chlordiazepoxide Professional Patient Advice (Wolters Kluwer)
  • chlordiazepoxide Concise Consumer Information (Cerner Multum)
  • chlordiazepoxide Advanced Consumer (Micromedex) - Includes Dosage Information
  • Librium Prescribing Information (FDA)

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