Cinryze Generic Name: C1 Inhibitor
(Human) (C1 in-HIB-i-ter)Brand Name:
Cinryze is used for:
Preventing angioedema attacks in patients with hereditary angioedema (HAE). It may also be used for other conditions as determined by your doctor.
Cinryze is a C1 inhibitor (human). It works by regulating the clotting and inflammatory reactions that can lead to local tissue swelling (angioedema).
Do NOT use Cinryze if:
- you are allergic to any ingredient in Cinryze
Contact your doctor or health care provider right away if any of these apply to you.
Before using Cinryze :
Some medical conditions may interact with Cinryze . Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:
- if you are pregnant, planning to become pregnant, or are breast-feeding
- if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
- if you have allergies to medicines, foods, or other substances
- if you have a history of blood clots in your veins or lungs (eg, deep vein thrombosis, pulmonary embolism)
Some MEDICINES MAY INTERACT with Cinryze . However, no specific interactions with Cinryze are known at this time.
Ask your health care provider if Cinryze may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.
How to use Cinryze :
Use Cinryze as directed by your doctor. Check the label on the medicine for exact dosing instructions.
- An extra patient leaflet is available with Cinryze . Talk to your pharmacist if you have questions about this information.
- Cinryze is usually given as an injection at your doctor's office, hospital, or clinic. If you will be using Cinryze at home, a health care provider will teach you how to use it. Be sure you understand how to use Cinryze . Follow the procedures you are taught when you use a dose. Contact your health care provider if you have any questions.
- Do not use Cinryze if it contains particles, is cloudy or discolored, or if the vial is cracked or damaged.
- This product must be used within 3 hours after mixing.
- Keep this product, as well as syringes and needles, out of the reach of children and pets. Do not reuse needles, syringes, or other materials. Ask your health care provider how to dispose of these materials after use. Follow all local rules for disposal.
- If you miss a dose of Cinryze , contact your doctor right away.
Ask your health care provider any questions you may have about how to use Cinryze .
Important safety information:
- Cinryze may contain albumin, which comes from human blood. There is a very rare risk of getting a viral disease or a central nervous system disease called Creutzfeldt-Jakob disease from products with albumin. No cases of these problems have been found in patients who have used Cinryze .
- Cinryze should be used with extreme caution in CHILDREN; safety and effectiveness in children have not been confirmed.
- PREGNANCY and BREAST-FEEDING: It is not known if Cinryze can cause harm to the fetus. If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Cinryze while you are pregnant. It is not known if Cinryze is found in breast milk. If you are or will be breast-feeding while you use Cinryze , check with your doctor. Discuss any possible risks to your baby.
Possible side effects of Cinryze :
All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:
Headache; stuffy or runny nose.Seek medical attention right away if any of these SEVERE side effects occur:
Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); changes in consciousness or speech; chest pain; dizziness or lightheadedness; fainting; fatigue; fever; numbness or tingling; severe or persistent headache; shortness of breath; sore throat; swelling or pain in the arms, legs, or stomach; weakness.
This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. You may also report side effects at http://www.fda.gov/medwatch.
If OVERDOSE is suspected:
Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (http://www.aapcc.org), or emergency room immediately. Symptoms may include changes in consciousness or speech; chest pain; numbness or tingling; shortness of breath; swelling or pain in the arms, legs, or stomach.Proper storage of Cinryze :
Cinryze is usually handled and stored by a health care provider. If you are using Cinryze at home, store Cinryze as directed by your pharmacist or health care provide. Keep Cinryze out of the reach of children and away from pets.
- If you have any questions about Cinryze , please talk with your doctor, pharmacist, or other health care provider.
- Cinryze is to be used only by the patient for whom it is prescribed. Do not share it with other people.
- If your symptoms do not improve or if they become worse, check with your doctor.
This information is a summary only. It does not contain all information about Cinryze . If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.
- Cinryze Prescribing Information (FDA)
- Cinryze Advanced Consumer (Micromedex) - Includes Dosage Information
- Cinryze Consumer Overview
- Berinert Prescribing Information (FDA)
- Berinert Consumer Overview