Ciprofloxacin (SIP-roe-FLOX-a-sin)Brand Name:
Ciprofloxacin are associated with an increased risk of tendon problems. These include pain, swelling, inflammation, and possible breakage of tendons. The risk of tendon problems is greater in patients who are over 60 years old, patients who take corticosteroids (eg, prednisone), and in those who have received kidney, heart, or lung transplants. The Achilles tendon in the back of the foot/ankle is most often affected. However, problems may also occur in other tendons (eg, in the shoulder, arm, hand). Problems may occur while you take Ciprofloxacin or up to several months after you stop taking it.
Signs of tendon problems may include pain, soreness, redness, or swelling of a tendon or joint; bruising right after an injury in a tendon area; hearing or feeling a snap or pop in a joint or tendon area; or inability to move or bear weight on a joint or tendon area. Tell your doctor right away if you experience any of these symptoms while you take Ciprofloxacin or within several months after you stop taking it.
Ciprofloxacin are used for:
Treating bacterial infections. It may also be used to prevent or slow anthrax after exposure.
Ciprofloxacin are a fluoroquinolone antibiotic used to kill sensitive bacteria. It works by stopping the production of essential proteins needed by the bacteria to survive.
Do NOT use Ciprofloxacin if:
- you are allergic to any ingredient in Ciprofloxacin or to any other fluoroquinolone (eg, levofloxacin)
- you are taking tizanidine or you have recently received a live oral typhoid vaccine
Contact your doctor or health care provider right away if any of these apply to you.
Before using Ciprofloxacin:
Some medical conditions may interact with Ciprofloxacin. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:
- if you are pregnant, planning to become pregnant, or are breast-feeding
- if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
- if you have allergies to medicines, foods, or other substances
- if you have a stomach infection, liver problems, brain or nervous system problems, increased pressure in the brain, Alzheimer disease, brain blood vessel problems, muscle problems (eg, myasthenia gravis), or a history of seizures
- if you have a history of severe or persistent diarrhea, skin sensitivity to the sun, low blood potassium levels, heart problems, irregular heartbeat (eg, QT prolongation), or if you have a family member with a history of irregular heartbeat
- if you have a history of joint or tendon problems; rheumatoid arthritis; kidney problems or decreased kidney function; or heart, kidney, or lung transplant
- if you take corticosteroids (eg, prednisone) or you participate in strenuous physical work or exercise
Some MEDICINES MAY INTERACT with Ciprofloxacin. Tell your health care provider if you are taking any other medicines, especially any of the following:
- Antiarrhythmics (eg, amiodarone, quinidine) because the risk of serious side effects, including irregular heartbeat, may be increased
- Corticosteroids (eg, prednisone) because they may increase the risk of tendon problems
- Diuretics (eg, furosemide, hydrochlorothiazide), metoclopramide, nonsteroidal anti-inflammatory drugs (NSAIDs) (eg, ibuprofen), or probenecid because they may increase the risk of Ciprofloxacin's side effects
- Anticoagulants (eg, warfarin), antipsychotics (eg, clozapine), cyclosporine, methotrexate, monoamine oxidase inhibitors (MAOIs) (eg, phenelzine), serotonin norepinephrine reuptake inhibitors (SNRIs) (eg, duloxetine), sulfonylureas (eg, glyburide), theophylline, tizanidine, tricyclic antidepressants (eg, amitriptyline), or xanthines (eg, caffeine) because the risk of their side effects may be increased by Ciprofloxacin
- Hydantoins (eg, phenytoin) or live oral typhoid vaccine because their effectiveness may be decreased by Ciprofloxacin
This may not be a complete list of all interactions that may occur. Ask your health care provider if Ciprofloxacin may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.
How to use Ciprofloxacin:
Use Ciprofloxacin as directed by your doctor. Check the label on the medicine for exact dosing instructions.
- An extra patient leaflet may be available with Ciprofloxacin. Talk to your pharmacist if you have questions about this information.
- Take Ciprofloxacin by mouth with or without food. The preferred dosing time is 2 hours after a meal.
- Take Ciprofloxacin with a full glass of water (8 oz/240 mL).
- Drinking extra fluids while you are taking Ciprofloxacin are recommended. Check with your doctor for instructions.
- If you also take any products containing magnesium, aluminum, calcium, iron, or zinc (eg, antacids, quinapril, vitamins/minerals); didanosine; sucralfate; or bismuth subsalicylate, do not take them within 6 hours before or 2 hours after taking Ciprofloxacin. Check with your doctor if you have questions.
- If you also take sevelamer, do not take it within 4 hours before or after taking Ciprofloxacin. Check with your doctor if you have questions.
- Ciprofloxacin works best if it is taken at the same time each day.
- To clear up your infection completely, take Ciprofloxacin for the full course of treatment. Keep taking it even if you feel better in a few days.
- Avoid taking Ciprofloxacin with milk or milk products (eg, calcium-enriched juice, yogurt) by themselves. However, taking Ciprofloxacin as part of a full meal that contains milk or milk products is permitted.
- Do not miss any doses. If you miss a dose of Ciprofloxacin, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.
Ask your health care provider any questions you may have about how to use Ciprofloxacin.
Important safety information:
- Ciprofloxacin may cause drowsiness, dizziness, blurred vision, or lightheadedness. These effects may be worse if you take it with alcohol or certain medicines. Use Ciprofloxacin with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.
- Be sure to use Ciprofloxacin for the full course of treatment. If you do not, the medicine may not clear up your infection completely. The bacteria could also become less sensitive to this or other medicines. This could make the infection harder to treat in the future.
- Long-term or repeated use of Ciprofloxacin may cause a second infection. Tell your doctor if signs of a second infection occur. Your medicine may need to be changed to treat this.
- Ciprofloxacin only works against bacteria; it does not treat viral infections (eg, the common cold).
- Avoid large amounts of food or drink that have caffeine (eg, coffee, tea, cocoa, cola, chocolate).
- Tell your doctor right away if you experience pain or swelling of a tendon or weakness or loss of use of a joint area. Rest the area and avoid exercise until further instruction from your doctor.
- Diabetes patients - Ciprofloxacin may affect your blood sugar. Check blood sugar levels closely. Ask your doctor before you change the dose of your diabetes medicine.
- Ciprofloxacin may cause you to become sunburned more easily. Avoid the sun, sunlamps, or tanning booths until you know how you react to Ciprofloxacin. Use a sunscreen or wear protective clothing if you must be outside for more than a short time.
- Mild diarrhea is common with antibiotic use. However, a more serious form of diarrhea (pseudomembranous colitis) may rarely occur. This may develop while you use the antibiotic or within several months after you stop using it. Contact your doctor right away if stomach pain or cramps, severe diarrhea, or bloody stools occur. Do not treat diarrhea without first checking with your doctor.
- Use Ciprofloxacin with caution in the ELDERLY; they may be more sensitive to its effects (eg, tendon problems), especially if they take corticosteroids (eg, prednisone). They may also be more sensitive to other effects (eg, irregular heartbeat).
- Ciprofloxacin should be used with extreme caution in CHILDREN younger than 18 years old; they may be more sensitive to its effects, especially joint and tendon problems.
- PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Ciprofloxacin while you are pregnant. Ciprofloxacin are found in breast milk. Do not breast-feed while taking Ciprofloxacin.
Possible side effects of Ciprofloxacin:
All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:
Diarrhea; dizziness; headache; loss of appetite; nausea; stomach upset; vomiting.Seek medical attention right away if any of these SEVERE side effects occur:
Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); bloody or tarry stools; burning, numbness, tingling, pain, or weakness of the arms, hands, legs, or feet; chest pain; dark urine or unusual change in amount of urine; fainting; fever, chills, or unusual cough; hallucinations; inability to move or bear weight on a joint or tendon area; irregular heartbeat; loss of consciousness; moderate to severe sunburn; mood or mental changes (eg, new or worsening anxiety, agitation, confusion, depression, restlessness, sleeplessness); muscle pain or weakness; pain, soreness, redness, swelling, weakness, or bruising of a tendon or joint area; pale stools; persistent sore throat; red, swollen, blistered, or peeling skin; seizures; severe or persistent diarrhea; severe or persistent dizziness; stomach cramps/pain; suicidal thoughts or actions; tremors; unusual bruising or bleeding; unusual fatigue; vaginal yeast infection; vision changes; yellowing of the skin or eyes.
This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. You may also report side effects at http://www.fda.gov/medwatch.
If OVERDOSE is suspected:
Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (http://www.aapcc.org), or emergency room immediately.Proper storage of Ciprofloxacin:
Store Ciprofloxacin at room temperature, between 59 and 86 degrees F (15 and 30 degrees C), in a tightly closed container. Store away from heat, moisture, and light. Do not store in the bathroom. Keep Ciprofloxacin out of the reach of children and away from pets.
- If you have any questions about Ciprofloxacin, please talk with your doctor, pharmacist, or other health care provider.
- Ciprofloxacin are to be used only by the patient for whom it is prescribed. Do not share it with other people.
- If your symptoms do not improve or if they become worse, check with your doctor.
This information is a summary only. It does not contain all information about Ciprofloxacin. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.
- Ciprofloxacin Prescribing Information (FDA)
- Ciprofloxacin Professional Patient Advice (Wolters Kluwer)
- ciprofloxacin Advanced Consumer (Micromedex) - Includes Dosage Information
- Cipro Prescribing Information (FDA)
- Cipro Detailed Consumer Information (PDR)
- Cipro Consumer Overview
- Cipro XR Prescribing Information (FDA)
- Proquin XR Prescribing Information (FDA)
- Proquin XR Detailed Consumer Information (PDR)
- Proquin XR Consumer Overview