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Drugs reference index «Cisplatin»



Generic Name: Cisplatin (sis-PLA-tin)Brand Name: Platinol AQ

Cisplatin can cause severe kidney problems or allergic reactions. Hearing loss (more common in children), bleeding problems, a decrease in your body's ability to fight infection (weakened immune system), or severe nausea and vomiting may also occur. The risk of these problems increases as the dose or total amount of Cisplatin used over time increases. Notify your doctor immediately if you develop changes in the amount of urine, rash, trouble breathing, swelling of the face, fast heartbeat, dizziness, ringing in the ears or hearing loss, unusual bruising or bleeding, nausea and vomiting, unusual tiredness, or signs of an infection (eg, fever, persistent sore throat).

Cisplatin is used for:

Treating cancer of the testes, ovaries, or bladder. Cisplatin may be used alone or in combination with other medications. It may also be used for other conditions as determined by your doctor.

Cisplatin is an antineoplastic agent. It works by stopping cancer cells from growing and reproducing.

Do NOT use Cisplatin if:

  • you are allergic to any ingredient in Cisplatin or other platinum-containing products
  • you have hearing problems, kidney problems, or a weakened immune system

Contact your doctor or health care provider right away if any of these apply to you.

Before using Cisplatin :

Some medical conditions may interact with Cisplatin . Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, planning to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances

Some MEDICINES MAY INTERACT with Cisplatin . Tell your health care provider if you are taking any other medicines, especially any of the following:

  • Bleomycin, iodine-containing radiopaque agents, or methotrexate because the risk of side effects may be increased
  • Ondansetron because the effectiveness of Cisplatin may be decreased
  • Carbamazepine, hydantoins (eg, phenytoin), or valproic acid because effectiveness may be decreased by Cisplatin

This may not be a complete list of all interactions that may occur. Ask your health care provider if Cisplatin may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Cisplatin :

Use Cisplatin as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • Cisplatin is administered as an injection at your doctor's office, hospital, or clinic.
  • If Cisplatin contains particles or is discolored, or if the vial is cracked or damaged in any way, do not use it.
  • Drinking extra fluids while you are taking Cisplatin is recommended, especially before and for 24 hours after you receive Cisplatin . Check with your doctor for instructions.
  • If Cisplatin accidentally spills on your skin, wash it off immediately with soap and water.
  • If nausea, vomiting, or loss of appetite occurs, ask your doctor or pharmacist for ways to lessen these effects.
  • Keep this product, as well as syringes and needles, out of the reach of children and away from pets. Do not reuse needles, syringes, or other materials. Dispose of properly after use. Ask your doctor or pharmacist to explain local regulations for proper disposal.
  • If you miss a dose of Cisplatin , contact your doctor immediately.

Ask your health care provider any questions you may have about how to use Cisplatin .

Important safety information:

  • Cisplatin may reduce the number of clot-forming cells (platelets) in your blood. To prevent bleeding, avoid situations in which bruising or injury may occur. Report any unusual bleeding, bruising, blood in stools, or dark, tarry stools to your doctor.
  • Cisplatin may lower your body's ability to fight infection. Prevent infection by avoiding contact with people with colds or other infections. Notify your doctor of any signs of infection, including fever, sore throat, rash, or chills.
  • Avoid vaccinations with live virus vaccines (eg, measles, mumps, oral polio) while you are taking Cisplatin . Vaccinations may be less effective.
  • LAB TESTS, including hearing tests, kidney function, and magnesium, sodium, potassium, and calcium blood levels, may be performed to monitor your progress or to check for side effects. Be sure to keep all doctor and lab appointments.
  • Use Cisplatin with caution in the ELDERLY because they may be more sensitive to its effects, especially the effects on the kidneys and blood cells.
  • Cisplatin is not recommended for use in CHILDREN. Safety and effectiveness have not been confirmed.
  • PREGNANCY and BREAST-FEEDING: Cisplatin has been shown to cause harm to the fetus. If you think you may be pregnant, discuss with your doctor the benefits and risks of using Cisplatin during pregnancy. Cisplatin is excreted in breast milk. Do not breast-feed while taking Cisplatin .

Possible side effects of Cisplatin :

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Diarrhea; loss of appetite; muscle pain; nausea; vomiting; weakness.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); blindness; blood in the urine or stools; blurred vision; chest pain; decreased urine volume or frequency; dizziness; hearing problems; inability to distinguish colors; infection (fever, chills, sore throat, cough); joint pain; lightheadedness; loss of balance; loss of motor function; loss of taste; numbness, tingling, or pain of the hands or feet; pain, redness, or swelling at the site of injection; ringing in the ears; seizures; unusual bruising or bleeding; unusual tiredness; wheezing.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. You may also report side effects at http://www.fda.gov/medwatch.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (http://www.aapcc.org), or emergency room immediately. Symptoms may include dark urine; deafness; decreased urination; nausea; vision impairment; vomiting; yellowing of the eyes or skin.

Proper storage of Cisplatin :

Store Cisplatin as directed on the prescription label. Cisplatin is usually handled and stored by a health care provider. If you are using Cisplatin at home, store Cisplatin as directed by your pharmacist or health care provider. Keep Cisplatin out of the reach of children and away from pets.

General information:

  • If you have any questions about Cisplatin , please talk with your doctor, pharmacist, or other health care provider.
  • Cisplatin is to be used only by the patient for whom it is prescribed. Do not share it with other people.
  • If your symptoms do not improve or if they become worse, check with your doctor.

This information is a summary only. It does not contain all information about Cisplatin . If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

  • Cisplatin Professional Patient Advice (Wolters Kluwer)
  • cisplatin Concise Consumer Information (Cerner Multum)
  • cisplatin Intravenous Advanced Consumer (Micromedex) - Includes Dosage Information

See Also...

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