Pronunciation: (KLOE-mih-feen SIH-trate)Class: Ovulation stimulant
Trade Names:Clomid- Tablets 50 mg
Trade Names:Milophene- Tablets 50 mg
Trade Names:Serophene- Tablets 50 mg
Induces ovulation in selected anovulatory women.
About 42% is excreted in feces; about 8% is excreted in urine. May still be detectable in feces 6 wk after administration. May exhibit enterohepatic recycling.
Indications and Usage
Treatment of ovulatory failure in women desiring pregnancy when partner is fertile and potent.
Treatment of male infertility.
Liver disease; history of liver dysfunction; abnormal bleeding of undetermined origin; pregnancy.
Dosage and AdministrationInitial Therapy
PO 50 mg/day for 5 days.Second and Third Courses
PO 100 mg/day for 5 days.
None well documented.
Laboratory Test Interactions
None well documented.
Headache, dizziness; lightheadedness.
Visual symptoms; blurring spots or flashes; diplopia; photophobia.
Abdominal pain/discomfort; distension; bloating; nausea; vomiting.
Abnormal uterine bleeding; abnormal ovarian enlargement, luteal cyst formation.
Notify health care provider if patient experiences abdominal pain, abnormal uterine bleeding, visual changes, or jaundice.
Category X .
May increase chance for multiple pregnancies.
May cause blurring of vision.
- Caution patient that this medication must not be taken during pregnancy or when pregnancy is possible. Advise patient to use reliable form of birth control while taking this drug.
- Counsel patient and partner in purpose of scheduling clomiphene citrate, sexual intercourse and ovulation time to be successful in achieving pregnancy.
- Advise women that increased midcycle ovarian discomfort may be experienced and can assist in planning intercourse.
- Instruct patient of importance of well-balanced diet, mild exercise routine, and avoidance of drugs, caffeine and alcohol while attempting to achieve pregnancy.
- Inform patient of possibility for multiple pregnancies.
- Explain that medication may cause dizziness, hot flashes, headache, nausea and weight gain but that these effects will subside after medication is stopped.
- Instruct patient to report these symptoms to health care provider: abnormal uterine bleeding, yellowish skin or eyes, blurred vision.
- Advise patient to use caution while driving or using heavy equipment because blurring of vision can occur.
Copyright © 2009 Wolters Kluwer Health.
- Clomid Prescribing Information (FDA)
- Clomid Consumer Overview
- Clomid Detailed Consumer Information (PDR)
- Clomid Advanced Consumer (Micromedex) - Includes Dosage Information
- Clomid MedFacts Consumer Leaflet (Wolters Kluwer)
- Clomiphene Prescribing Information (FDA)
- Serophene Prescribing Information (FDA)
- Serophene Detailed Consumer Information (PDR)