Generic name: Balsalazide disodiumBrand names: Colazal
Colazal is used in the treatment of mild to moderate ulcerative colitis (chronic inflammation and ulceration of the lower intestine). It is an anti-inflammatory medicine specially formulated to release the active ingredient, mesalamine, directly to the lining of the colon. Its ability to provide relief without the severe side effects found with similar drugs is believed to be due to this localized drug delivery mechanism.
Although there have been no reports of kidney damage from Colazal, other products containing mesalamine are known to have caused this problem. If you have kidney disease, your doctor will monitor your condition closely during treatment with Colazal. Report any problems or unusual symptoms immediately.
Colazal can be taken with or without food.
Side effects cannot be anticipated. If any develop or change in intensity, inform your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking Colazal.
Do not take Colazal if you are allergic to mesalamine or salicylates such as aspirin.
Some cases of fatal liver disease have been reported during treatment with Colazal. If you have a liver problem, make sure your doctor is aware of it before you start treatment.
If you have pyloric stenosis (narrowing of the stomach outlet), Colazal capsules may be slow to pass through the digestive tract.
Although many people get significant relief from Colazal, you should be aware that in rare cases it makes the symptoms worse.
This drug has not been tested in children.
While drug interactions with Colazal have not yet been studied, it is possible that oral antibiotics could interfere with the release of Colazal in the colon.
The effects of Colazal during pregnancy have not been adequately studied. If you are pregnant or plan to become pregnant, notify your doctor before taking Colazal. It should be used during pregnancy only if clearly needed.
It is not known whether Colazal appears in breast milk. Because there's a chance that it may, caution is advised.
The usual dose of Colazal is three 750-milligram capsules taken 3 times daily for 8 to 12 weeks.
Little is known about Colazal overdose. However, any drug taken in excess can have serious consequences. If you suspect an overdose, seek emergency medical treatment immediately.