Trade Names:Coly-Mycin S Otic- Suspension 1% hydrocortisone, 4.71 mg neomycin sulfate (equiv. to 3.3 mg neomycin base), 3 mg colistin (as sulfate), and 0.05% thonzonium bromide/mL
Trade Names:Cortisporin-TC Otic- Suspension 1% hydrocortisone, 3.3 mg neomycin sulfate, 3 mg colistin (as sulfate), and 0.5 mg thonzonium bromide
Bactericidal agent against most gram-negative organisms, particularly, Pseudomonas aeruginosa .Neomycin
Inhibits protein synthesis by binding to ribosomal RNA, causing bacterial genetic code misreading.Thonzonium
Surface-active agent that promotes tissue contact by dispersion and penetration of the cellular debris and exudates.Hydrocortisone
Depresses formation, release, and activity of endogenous mediators of inflammation as well as modifying body's immune response.
Treatment of superficial bacterial infections of the external auditory canal caused by susceptible organisms; treatment of infection of mastoidectomy and fenestration cavities caused by susceptible organisms.
Sensitivity to any component of the product; external auditory canal disorder caused by cutaneous viral infections (eg, herpes simplex virus, varicella zoster virus).
Otic Thoroughly clean external auditory canal and dry with sterile cotton applicator. Using the calibrated dropper, instill 5 drops of the suspension into affected ear 3 or 4 times daily.Children
Otic Thoroughly clean external auditory canal and dry with sterile cotton applicator. Using the calibrated dropper, instill 4 drops of the suspension into affected ear 3 or 4 times daily. Alternatively, a cotton wick may be inserted into the canal and then saturated with the suspension. The wick may be kept moist by adding additional solution every 4 h. Replace wick at least once every 24 h.
Store at controlled room temperature (59° to 86°F).
None well documented.
None well documented.
Cutaneous sensitization (particularly neomycin).
Monitor patient for improvement of symptoms of infection.Sensitivity
Monitor patient for sensitization or irritation and report to health care provider if noted.
Prolonged use may result in bacterial or fungal overgrowth of nonsusceptible microorganisms.
Bacterial resistance to components of the product may develop.
Allergic cross-sensitivity may occur, which could prevent future use of the following antibiotics: kanamycin, paromomycin, streptomycin, and possibly gentamicin.
Use with caution because of possibility of neomycin-induced ototoxicity.
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