Generic Name: aminoglutethimide (ah mee no glue TEH tha mide)Brand Names: Cytadren
Aminoglutethimide is an anti-hormone medication. Aminoglutethimide interferes with the body's production of certain hormones.
Aminoglutethimide is used in the treatment of conditions which cause the body to make too much of certain hormones (Cushing's syndrome).
Aminoglutethimide may also be used for purposes other than those listed in this medication guide.What is the most important information I should know about Cytadren (aminoglutethimide)?
Aminoglutethimide should only be administered under the supervision of a qualified healthcare provider experienced with its use and hazards. Treatment should usually begin in a hospital.Use caution when driving, operating machinery, or performing other hazardous activities. Aminoglutethimide may cause drowsiness and dizziness. If you experience drowsiness or dizziness, avoid these activities. Use alcohol cautiously. Alcohol may increase the effects of aminoglutethimide.
Aminoglutethimide may stop your body from responding to conditions of stress, such as surgery, injury, or sudden illness. Talk to your doctor about the possible side effects from treatment with aminoglutethimide.What should I discuss with my healthcare provider before taking Cytadren (aminoglutethimide)?Do not use aminoglutethimide without first talking to your doctor if you have recently had:
a serious injury;
a serious illness.
You may not be able to use aminoglutethimide, or you may require a dosage adjustment or special monitoring during treatment if you have any of the conditions listed above.Aminoglutethimide is in the FDA pregnancy category D. This means that it is known to be harmful to an unborn baby. Do not use aminoglutethimide without first talking to your doctor if you are pregnant or could become pregnant during treatment. Discuss with your doctor the appropriate use of birth control during treatment. It is not known whether aminoglutethimide passes into breast milk. Do not take aminoglutethimide without first talking to your doctor if you are breast feeding a baby.
Aminoglutethimide should only be administered under the supervision of a qualified healthcare provider experienced with its use and hazards. Treatment should usually begin in a hospital.Take each oral dose with a full glass of water.
Your doctor will determine the correct amount and frequency of treatment with aminoglutethimide depending upon your condition. Talk to your doctor if you have any questions or concerns regarding the treatment schedule.
Your doctor will probably want you to have regularly scheduled blood tests and other medical evaluations during treatment with aminoglutethimide to monitor progress and side effects.Store aminoglutethimide at room temperature away from moisture and heat.
Take the missed dose as soon as you remember. However, if it is almost time for the next regularly scheduled dose, skip the dose you missed and take only the next dose as directed. Do not take a double dose. A double dose of this medication could be dangerous.
Symptoms of a aminoglutethimide overdose may include decreased breathing, dizziness, fainting, sleepiness, poor coordination, weakness, coma, nausea, and vomiting.
If you experience any of the following serious side effects from aminoglutethimide, contact your doctor immediately:
an allergic reaction (including difficulty breathing; closing of the throat; swelling of the lips, tongue, or face; or hives); or
fainting or dizziness, especially when standing up.
Other, less serious side effects may be more likely to occur. Continue taking aminoglutethimide and talk to your doctor if you experience:
dizziness, drowsiness, poor coordination, or weakness;
nausea, vomiting, or loss of appetite;
rash and itching.
Other side effects have also been reported. Discuss with your doctor any side effect that occurs during treatment with aminoglutethimide.
Before using aminoglutethimide, tell your doctor if you are taking any of the following:
dexamethasone (Adrenocot, Dalalone, Decadron, Decaject, De-Sone, Dexacorten, Dexacort-LA, Dexamethasone Intensol, Dexasone, Dexone, Hexadrol, Medidex, Primethasone, Solurex, others); or
warfarin (Coumadin, others).
You may not be able to take aminoglutethimide, or you may require a dosage adjustment or special monitoring during treatment if you are taking any of the drugs listed above.
Drugs other than those listed here may also interact with aminoglutethimide. Talk to your doctor and pharmacist before taking any other prescription or over-the-counter medicines, including herbal products, during treatment with aminoglutethimide.
Aminoglutethimide is available with a prescription under the brand name Cytadren. Other brand or generic formulations may also be available. Ask your healthcare provider or pharmacist any questions you have about this medication, especially if it is new to you.