Generic Name: cytarabine liposomal (sye TAR a been lye poe SOE mal)Brand Names: DepoCyt
Cytarabine liposomal is a cancer medication. Cytarabine liposomal interferes with the growth of cancer cells and slows their growth and spread in the body.
Cytarabine liposomal is used to treat lymphoma associated with meningitis.
Cytarabine liposomal may also be used for other purposes not listed in this medication guide.
Before you receive cytarabine liposomal, tell your doctor about all of your medical conditions and any other medications you use. You may need a dose adjustment or special tests to safely use cytarabine liposomal:Tell your caregivers at once if you have nausea and vomiting with headache and fever. These may be early signs of central nervous system damage. Call your doctor at once if you have a serious side effect such as neck stiffness or pain, extreme drowsiness, confusion, personality changes, seizure, loss of muscle control, problems with vision or hearing, severe numbness or tingling, or loss of bladder or bowel control.What should I discuss with my healthcare provider before receiving cytarabine liposomal?You should not receive this medication if you are allergic to cytarabine liposomal or if you have an active meningitis infection.
Before you receive cytarabine liposomal, tell your doctor about all of your medical conditions and any other medications you use. You may need a dose adjustment or special tests to safely use cytarabine liposomal:FDA pregnancy category D. This medication can cause harm to an unborn baby. Do not receive cytarabine liposomal without telling your doctor if you are pregnant. Use an effective form of birth control, and tell your doctor if you become pregnant during treatment. It is not known whether cytarabine liposomal passes into breast milk or if it could harm a nursing baby. You should not breast-feed while being treated with cytarabine liposomal.
Cytarabine liposomal is given as an injection through a needle placed into the space around your spinal cord. You will receive this injection in a clinic or hospital setting.Tell your caregivers at once if you have nausea and vomiting with headache and fever. These may be early signs of central nervous system damage. To be sure cytarabine liposomal is not causing harmful effects, your doctor will need to check your progress on a regular basis. Do not miss any follow-up appointments.
Contact your doctor for instructions if you miss an appointment for your cytarabine liposomal injection.
Overdose symptoms may include nausea, vomiting, headache and fever, confusion, and changes in personality or behavior.
Follow your doctor's instructions about any restrictions on food, beverages, or activity.
nausea and vomiting with headache and fever;
neck stiffness or pain, seizure (convulsions);
extreme drowsiness, loss of muscle control;
confusion, personality changes, problems with memory or concentration, sleep problems, agitation;
problems with speech, vision, hearing, or balance,
numbness, tingling, or burning pain that interferes with daily activities;
loss of bladder or bowel control;
pale skin, feeling light-headed or short of breath, rapid heart rate;
easy bruising, unusual bleeding (nose, mouth, vagina, or rectum), purple or red pinpoint spots under your skin; or
flu symptoms, sores in your mouth and throat.
Less serious side effects may include:
mild nausea or vomiting;
diarrhea, constipation, stomach pain;
swelling in your hands or feet;
dizziness, tired feeling;
joint pain, back pain; or, arm or leg pain; or
pain in your arms or legs.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Usual Adult Dose for Meningitis -- Lymphomatous:
Cytarabine liposomal for the intrathecal treatment of lymphomatous meningitis:Induction Therapy: cytarabine liposome injection 50 mg, administered intrathecally (intraventricular or lumbar puncture) every 14 days for 2 doses (weeks 1 and 3). Consolidation Therapy: cytarabine liposome injection 50 mg, administered intrathecally (intraventricular or lumbar puncture) every 14 days for 3 doses (weeks 5, 7 and 9) followed by one additional dose at week 13. Maintenance: cytarabine liposome injection 50 mg, administered intrathecally (intraventricular or lumbar puncture) every 28 days for 4 doses (weeks 17, 21, 25 and 29).
There may be other drugs that can interact with cytarabine liposomal. Tell your doctor about all your prescription and over-the-counter medications, vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start a new medication without telling your doctor.