Dacarbazine can cause severe, even fatal, liver problems (hepatic necroses), or a decrease in the formation of new blood cells (hemopoietic depression). It has also caused cancer and birth defects in laboratory animals. Notify your doctor immediately if you develop symptoms of an infection (eg, persistent sore throat or fever), easy bruising or bleeding, nausea, dark urine, unusual fatigue, yellowing of the eyes or skin, or stomach pain. Your doctor will monitor you closely while you are using Dacarbazine .
Treating certain cancers (eg, advanced skin cancer) and Hodgkin disease. It may be used with other medicines. It may also be used for other conditions as determined by your doctor.
Dacarbazine is an antineoplastic agent. It is not known exactly how Dacarbazine works. It may block the growth of cancer cells.
Contact your doctor or health care provider right away if any of these apply to you.
Some medical conditions may interact with Dacarbazine . Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:
Some MEDICINES MAY INTERACT with Dacarbazine . However, no specific interactions with Dacarbazine are known at this time.
This may not be a complete list of all interactions that may occur. Ask your health care provider if Dacarbazine may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.
Use Dacarbazine as directed by your doctor. Check the label on the medicine for exact dosing instructions.
Ask your health care provider any questions you may have about how to use Dacarbazine .
All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:
Facial flushing, numbness, or tingling; loss of appetite; metallic taste in mouth; muscle pain or weakness; nausea; temporary hair loss; vomiting.
Seek medical attention right away if any of these SEVERE side effects occur:Severe allergic reactions (rash; hives; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); dark urine; fever, chills, or sore throat; joint pain; pain, redness, or swelling at injection site; severe nausea and vomiting; stomach pain; unusual bruising or bleeding; unusual tiredness or weakness; yellowing of skin or eyes.
This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. You may also report side effects at http://www.fda.gov/medwatch.
Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (http://www.aapcc.org), or emergency room immediately.
Proper storage of Dacarbazine :Dacarbazine is usually handled and stored by a health care provider. If you are using Dacarbazine at home, store Dacarbazine as directed by your pharmacist or health care provider. Keep Dacarbazine , as well as needles and syringes, out of the reach of children and away from pets.
This information is a summary only. It does not contain all information about Dacarbazine . If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.