Dantrolene Capsules may cause serious, even fatal, liver problems, especially when used in larger amounts (800 mg/day or more). This side effect has occurred even in people who have taken Dantrolene Capsules for a short period of time. The risk appears to be greater in women, people older than 35 years of age, people between their 3rd and 12th month of taking Dantrolene Capsules, and people using other medicines at the same time. Lab tests, such as liver function tests, will be performed to check for side effects. Promptly notify your doctor if you have signs of liver problems, such as yellowing of the eyes or skin, dark urine, severe stomach or abdominal pain, or unusual fatigue.
Treating spasms (spasticity) caused by nerve disorders, such as stroke, cerebral palsy, spinal cord injury, or multiple sclerosis. It may be used prevent or reduce the risk of severe high body temperature (malignant hyperthermia) in certain patients before surgery or anesthesia. It may be used after an episode of severe high body temperature to prevent future episodes. It may also be used for other conditions as determined by your doctor.
Dantrolene Capsules are a muscle relaxant. It works by interfering with the release of certain substances that are needed by the muscles for contraction, or by restoring a healthy level of calcium in the muscles, which helps to prevent or reduce severe high body temperature.
Contact your doctor or health care provider right away if any of these apply to you.
Some medical conditions may interact with Dantrolene Capsules. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:
Some MEDICINES MAY INTERACT with Dantrolene Capsules. Tell your health care provider if you are taking any other medicines, especially any of the following:
This may not be a complete list of all interactions that may occur. Ask your health care provider if Dantrolene Capsules may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.
Use Dantrolene Capsules as directed by your doctor. Check the label on the medicine for exact dosing instructions.
Ask your health care provider any questions you may have about how to use Dantrolene Capsules.
All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:
Diarrhea; dizziness; drowsiness; general body discomfort; nausea; sensitivity to sunlight; unusual tiredness; vision changes; weakness.Seek medical attention right away if any of these SEVERE side effects occur:
Severe allergic reactions (rash; hives; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); blood in the urine; bloody or black, tarry stools; chest pain; coffee ground-like vomit; confusion; dark urine; depression; difficulty urinating; fast heartbeat; fever or chills; seizures; severe or persistent diarrhea; severe stomach or abdominal pain; shortness of breath; unusual tiredness; vomiting; yellowing of the skin or eyes.
This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. You may also report side effects at http://www.fda.gov/medwatch.
Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (http://www.aapcc.org), or emergency room immediately.Proper storage of Dantrolene Capsules:
Store at room temperature, between 68 and 77 degrees F (20 and 25 degrees C). Store away from light, heat, and moisture. Do not store in the bathroom. Keep Dantrolene Capsules out of the reach of children and away from pets.
This information is a summary only. It does not contain all information about Dantrolene Capsules. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.