Desmopressin SprayGeneric Name:
Desmopressin (DES-moe-PRES-in)Brand Name:
Desmopressin Spray is used for:
Treating bleeding episodes in patients with certain types of hemophilia or von Willebrand disease. It may also be used for other conditions as determined by your doctor.
Desmopressin Spray is an antidiuretic hormone. It works by increasing the amount of a blood factor necessary for normal blood clotting.
Do NOT use Desmopressin Spray if:
- you are allergic to any ingredient in Desmopressin Spray
- you have type IIB von Willebrand disease
- you have or have a history of low blood sodium levels (salt depletion)
Contact your doctor or health care provider right away if any of these apply to you.
Before using Desmopressin Spray:
Some medical conditions may interact with Desmopressin Spray. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:
- if you are pregnant, planning to become pregnant, or are breast-feeding
- if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
- if you have allergies to medicines, foods, or other substances
- if you have nasal problems (eg, scarring, swelling, congestion, blockage, discharge, severe runny nose)
- if you have a history of kidney problems, heart problems (eg, heart blood vessel problems), abnormal blood clots (eg, in the legs, lungs, eyes), or high blood pressure
- if you have cystic fibrosis, dehydration, fever, severe infection, vomiting or diarrhea, swelling or fluid retention, or abnormal blood electrolyte levels
- if you are exposed to very hot weather, are physically active, or drink a lot of water
Some MEDICINES MAY INTERACT with Desmopressin Spray. Tell your health care provider if you are taking any other medicines, especially any of the following:
- Carbamazepine, chlorpromazine, lamotrigine, narcotic analgesics (eg, codeine), nonsteroidal anti-inflammatory drugs (NSAIDs) (eg, ibuprofen), oxybutynin, selective serotonin reuptake inhibitors (SSRIs) (eg, fluoxetine), or tricyclic antidepressants (eg, imipramine) because the risk of fluid overload with low blood sodium levels may be increased
This may not be a complete list of all interactions that may occur. Ask your health care provider if Desmopressin Spray may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.
How to use Desmopressin Spray:
Use Desmopressin Spray as directed by your doctor. Check the label on the medicine for exact dosing instructions.
- Carefully read and follow the patient instructions for use of the spray pump before using Desmopressin Spray.
- Desmopressin Spray is to be used only in the nose.
- The pump must be primed before the first use. To prime the pump, point the nozzle away from yourself and others. Press down 4 times.
- If the pump has not been used for 1 week or more, re-prime the pump by pressing down 1 time.
- Be sure to replace the protective cap on the bottle after each dose.
- Throw the bottle away after 25 sprays. It may no longer give the correct amount of medicine with each spray. Do not try to transfer the remaining medicine to another bottle.
- If you miss a dose of Desmopressin Spray, use it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not use 2 doses at once.
Ask your health care provider any questions you may have about how to use Desmopressin Spray.
Important safety information:
- Desmopressin Spray may cause drowsiness or dizziness. These effects may be worse if you take it with alcohol or certain medicines. Use Desmopressin Spray with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.
- Very carefully follow the fluid intake instructions given to you by your doctor. Serious side effects may occur if you drink too much liquid while taking Desmopressin Spray, especially in children and elderly patients.
- Check with your doctor if you experience infection, fever, vomiting, or diarrhea. Tell your doctor if you will be exposed to very hot weather, will be physically active, or will be increasing your water intake for any reason. The risk of low blood sodium levels may be increased.
- Do NOT use more than the recommended dose or use more often than prescribed without checking with your doctor. If bleeding is not controlled, contact your doctor.
- Lab tests, including blood electrolyte levels, blood clotting factor, or kidney function, may be performed while you use Desmopressin Spray. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.
- Use Desmopressin Spray with caution in the ELDERLY; they may be more sensitive to its effects. They should carefully follow limited fluid intake according to their doctor's instructions.
- Desmopressin Spray should not be used in CHILDREN younger than 11 months old; safety and effectiveness in these children have not been confirmed.
- PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Desmopressin Spray while you are pregnant. It is not known if Desmopressin Spray is found in breast milk. If you are or will be breast-feeding while you are using Desmopressin Spray, check with your doctor. Discuss any possible risks to your baby.
Possible side effects of Desmopressin Spray:
All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:
Cough; nosebleed; sore throat.Seek medical attention right away if any of these SEVERE side effects occur:
Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); calf pain, tenderness, or swelling; chest pain; confusion; coughing up blood; fainting; fast or irregular heartbeat; loss of appetite; mental or mood changes (eg, agitation); muscle weakness, spasms, or cramps; nausea; one-sided numbness or weakness; personality changes; scarring or swelling of the nose; seizures; severe or persistent headache or dizziness; severe, persistent, or recurring nosebleed; slurred speech; swelling (eg, of the hands or feet); swelling of the head of the penis; unusual tiredness or sluggishness; unusual weight gain; vision problems; vomiting.
This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. You may also report side effects at http://www.fda.gov/medwatch.
If OVERDOSE is suspected:
Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (http://www.aapcc.org), or emergency room immediately. Desmopressin Spray may be harmful if swallowed.Proper storage of Desmopressin Spray:
Store Desmopressin Spray in the refrigerator, between 36 and 46 degrees F (2 and 8 degrees C). Do not freeze. If you will be traveling, you may store Desmopressin Spray at room temperature, below 72 degrees F (22 degrees C) for up to 3 weeks. Store away from heat, moisture, and light. Store the bottle in an upright position. Keep Desmopressin Spray out of the reach of children and away from pets.
- If you have any questions about Desmopressin Spray, please talk with your doctor, pharmacist, or other health care provider.
- Desmopressin Spray is to be used only by the patient for whom it is prescribed. Do not share it with other people.
- If your symptoms do not improve or if they become worse, check with your doctor.
This information is a summary only. It does not contain all information about Desmopressin Spray. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.
- Desmopressin Prescribing Information (FDA)
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