Drugs Information Online
Drugs and diseases reference index

Drugs and diseases reference index
Search
EN

Drugs reference index «Agrylin»

Agrylin


Agrylin

Generic Name: anagrelide (Oral route)

an-AG-re-lide

Commonly used brand name(s):

In the U.S.

  • Agrylin

Available Dosage Forms:

  • Capsule

Therapeutic Class: Platelet Reducing Agent

Uses For Agrylin

Anagrelide is used to decrease the risk of blood clots in patients who have too many platelet cells in their blood.

This medicine is available only with your doctor's prescription.

Before Using Agrylin

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

This medicine has been tested in children and, in effective doses, has not been shown to cause different side effects or problems than it does in adults.

Pregnancy

Pregnancy CategoryExplanation
All TrimestersCAnimal studies have shown an adverse effect and there are no adequate studies in pregnant women OR no animal studies have been conducted and there are no adequate studies in pregnant women.

Breast Feeding

There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

Interactions with Medicines

Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

  • Desvenlafaxine
  • Duloxetine
  • Milnacipran
  • Venlafaxine

Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

  • Aspirin

Interactions with Food/Tobacco/Alcohol

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.

Other Medical Problems

The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially:

  • Heart disease (known or suspected)—Anagrelide can cause unwanted effects on the heart
  • Kidney disease—Anagrelide rarely causes unwanted effects on the kidney
  • Liver disease—Blood levels of anagrelide may be increased, possibly increasing the chance of side effects. Also, this medicine sometimes causes unwanted effects on the liver

Proper Use of Agrylin

Dosing

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

  • For oral dosage form (capsules):
    • For too many platelets in the blood:
      • Adults—0.5 milligrams (mg) four times a day, or 1 mg two times a day, for at least one week. After that, the dose is adjusted to the dose that keeps the number of platelets normal.
      • Children—0.5 mg one time per day, for at least one week. After that, the dose is adjusted to the dose that keeps the number of platelets normal.

Storage

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Precautions While Using Agrylin

It is very important that your doctor check your progress at regular visits to make sure that this medicine is working properly and to check for unwanted effects.

Anagrelide can cause unwanted effects on the heart, including a heart attack. Check with your doctor and/or get emergency help immediately if you experience any signs or symptoms of a heart attack.

Agrylin Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

Less common
  • Sudden severe headache or weakness
  • symptoms of a heart attack, which may include anxiety, cold sweating, increased heart rate, nausea or vomiting, severe pain or pressure in the chest and/or the jaw, neck, back, or arms, and shortness of breath

Check with your doctor as soon as possible if any of the following side effects occur:

More common
  • Abdominal or stomach pain
  • dizziness
  • irregular heartbeat
  • weakness
Less common
  • Blood in urine
  • blurred or double vision
  • difficulty in breathing
  • faintness
  • flushing
  • numbness or tingling in hands or feet
  • painful or difficult urination
  • swelling of feet or lower legs
  • unusual bleeding or bruising
  • unusual tiredness

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common
  • Diarrhea
  • gas or bloating of stomach
  • headache
  • heartburn
  • pain
Less common or rare
  • Back pain
  • canker sore
  • confusion
  • constipation
  • fever or chills
  • general feeling of discomfort or illness
  • joint pain
  • leg cramps
  • loss of appetite
  • mental depression
  • muscle pain
  • nervousness
  • ringing in the ears
  • skin rash or itching
  • sleepiness
  • stuffy or runny nose
  • trouble in sleeping
  • unusual sensitivity to light

Anagrelide may cause a temporary loss of hair in some people.

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

The information contained in the Thomson Healthcare (Micromedex) products as delivered by Drugs.com is intended as an educational aid only. It is not intended as medical advice for individual conditions or treatment. It is not a substitute for a medical exam, nor does it replace the need for services provided by medical professionals. Talk to your doctor, nurse or pharmacist before taking any prescription or over the counter drugs (including any herbal medicines or supplements) or following any treatment or regimen. Only your doctor, nurse, or pharmacist can provide you with advice on what is safe and effective for you.

The use of the Thomson Healthcare products is at your sole risk. These products are provided "AS IS" and "as available" for use, without warranties of any kind, either express or implied. Thomson Healthcare and Drugs.com make no representation or warranty as to the accuracy, reliability, timeliness, usefulness or completeness of any of the information contained in the products. Additionally, THOMSON HEALTHCARE MAKES NO REPRESENTATION OR WARRANTIES AS TO THE OPINIONS OR OTHER SERVICE OR DATA YOU MAY ACCESS, DOWNLOAD OR USE AS A RESULT OF USE OF THE THOMSON HEALTHCARE PRODUCTS. ALL IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE OR USE ARE HEREBY EXCLUDED. Thomson Healthcare does not assume any responsibility or risk for your use of the Thomson Healthcare products.

  • Agrylin Prescribing Information (FDA)
  • Agrylin MedFacts Consumer Leaflet (Wolters Kluwer)
  • Agrylin Concise Consumer Information (Cerner Multum)
  • Anagrelide Prescribing Information (FDA)
  • Anagrelide Professional Patient Advice (Wolters Kluwer)

Comment «Agrylin»