Generic name: AcetazolamideBrand names: Diamox
Diamox controls fluid secretion. It is used in the treatment of glaucoma (excessive pressure in the eyes), epilepsy (for both brief and unlocalized seizures), and fluid retention due to congestive heart failure or drugs. It is also used to prevent or relieve the symptoms of acute mountain sickness in climbers attempting a rapid climb and those who feel sick even though they are making a gradual climb.
This drug is considered to be a sulfa drug because of its chemical properties. Although rare, severe reactions have been reported with sulfa drugs. If you develop a rash, bruises, sore throat, or fever contact your doctor immediately.
Take Diamox exactly as prescribed by your doctor.
Side effects cannot be anticipated. If any develop or change in intensity, inform your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking Diamox.
Your doctor will not prescribe Diamox for you if your sodium or potassium levels are low, or if you have kidney or liver disease, including cirrhosis.
Diamox should not be used as a long-term treatment for the type of glaucoma called chronic noncongestive angle-closure glaucoma.
Be very careful about taking high doses of aspirin if you are also taking Diamox. Effects of this combination can range from loss of appetite, sluggishness, and rapid breathing to unresponsiveness; the combination can be fatal.
If you have emphysema or other breathing disorders, use Diamox with caution.
If you are taking Diamox to help in rapid ascent of a mountain, you must still come down promptly if you show signs of severe mountain sickness.
If Diamox is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your doctor before combining Diamox with the following:AmitriptylineAmphetamines such as dextroamphetamineAspirinCyclosporineLithiumMethenamineOral diabetes drugs such as glyburideQuinidine
The effects of Diamox during pregnancy have not been adequately studied. If you are pregnant or plan to become pregnant, inform your doctor immediately. Diamox may appear in breast milk and could affect a nursing infant. If Diamox is essential to your health, your doctor may advise you to discontinue breastfeeding until your treatment with Diamox is finished.
This medication is available in both oral and injectable form. Dosages are for the oral form only.
This medication is used as an addition to regular glaucoma treatment. Dosages for open-angle glaucoma range from 250 milligrams to 1 gram per 24 hours in 2 or more smaller doses. Your doctor will supervise your dosage and watch the effect of Diamox carefully if you are using it for glaucoma. In secondary glaucoma and before surgery in acute congestive (closed-angle) glaucoma, the usual dosage is 250 milligrams every 4 hours or, in some cases, 250 milligrams twice a day. Some people may take 500 milligrams to start, and then 125 or 250 milligrams every 4 hours. The injectable form of Diamox is occasionally used in acute cases.
The usual dosage of Diamox Sequels (sustained-release capsules) is 1 capsule (500 milligrams) twice a day, usually in the morning and evening.
Your doctor may adjust the dosage, as needed.
The daily dosage is 8 to 30 milligrams per 2.2 pounds of body weight in 2 or more doses. Typical dosage may range from 375 to 1,000 milligrams per day. Your doctor will adjust the dosage to suit your needs; Diamox can be used with other anticonvulsant medication.
Congestive Heart Failure
The usual starting dosage to reduce fluid retention in people with congestive heart failure is 250 milligrams to 375 milligrams per day or 5 milligrams per 2.2 pounds of body weight, taken in the morning. Diamox works best when it is taken every other day—or 2 days on, 1 day off—for this condition.
Edema Due to Medication
The usual dose is 250 milligrams to 375 milligrams daily for 1 or 2 days, alternating with a day of rest.
Acute Mountain Sickness
The usual dose is 500 milligrams to 1,000 milligrams a day in 2 or more doses, using either tablets or sustained-release capsules. Doses of Diamox are often begun 1 or 2 days before attempting to reach high altitudes.
The safety and effectiveness of Diamox in children have not been established. However, doses of 8 milligrams to 30 milligrams per 2.2 pounds of body weight have been used in children with various forms of epilepsy.
There is no specific information available on Diamox overdose, but any medication taken in excess can have serious consequences. If you suspect an overdose, seek medical attention immediately.