Generic Name: digoxin immune FAB (di JOX in im MYOON FAB)Brand Names: Digibind, DigiFab
Digoxin immune FAB is used as an antidote to treat a life-threatening overdose of digoxin or digitoxin.
Digoxin immune FAB is not for treating a mild digitalis overdose.
Digoxin immune FAB may also be used for other purposes not listed in this medication guide.What is the most important information I should know about DigiFab (digoxin immune FAB)?If possible, before you receive digoxin immune FAB, tell your doctor if you have heart disease or kidney disease, or if you are allergic to antibiotics or papaya extracts such as papain or chymopapain.
In an emergency situation, it may not be possible before you are treated to tell your caregivers about any health conditions you have or if you are pregnant or breast-feeding. However, make sure any doctor caring for you afterward knows that you received this medication.
After treatment with digoxin immune FAB, you will be watched to make sure the medication has been effective and you no longer have any effects of the digitalis overdose.What should I discuss with my health care provider before receiving DigiFab (digoxin immune FAB)?If possible, before you receive digoxin immune FAB, tell your doctor if you have:
if you are allergic to antibiotics; or
if you are allergic to papaya extracts such as papain or chymopapain (Chymodiactin).
In a poisoning situation, it may not be possible to tell your caregivers that you are pregnant or breast-feeding before you are treated with digoxin immune FAB. However, make sure any doctor caring for your pregnancy or your baby knows that you have received the medication.
Digoxin immune FAB is given as an injection through a needle placed into a vein. You will receive this injection in a hospital or emergency setting. The medicine must be given slowly through an IV infusion, and each dose can take up to 30 minutes to complete.
To be sure this medication is helping your condition and not causing harmful side effects, your blood will need to be tested on a regular basis. This will help your doctor determine how long to treat you with digoxin immune FAB.
This medication can cause you to have unusual results with certain digitalis tests. Tell any doctor who treats you that you have been treated with digoxin immune FAB.
Since digoxin immune FAB is given in an emergency situation by a healthcare professional, it is not likely that you will miss a dose.
An overdose of this medication is unlikely since it is given by a healthcare provider.
Follow your doctor's instructions about any restrictions on food, beverages, or activity after you are treated with digoxin immune FAB.
high potassium (slow heart rate, weak pulse, muscle weakness, tingly feeling);
low potassium (confusion, uneven heart rate, extreme thirst, increased urination, leg discomfort, muscle weakness or limp feeling);
feeling short of breath, even with mild exertion; or
swelling, rapid weight gain.
This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect. You may report side effects to FDA at 1-800-FDA-1088.
This list is not complete and there may be other drugs that can interact with digoxin immune FAB. Tell your doctor about all your prescription and over-the-counter medications, vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start a new medication without telling your doctor.