Generic Name: propofol (PROE poe fol)Brand Names: Diprivan
Propofol slows the activity of your brain and nervous system.
Propofol is used to help you relax before and during general anesthesia for surgery or other medical procedure. Propofol is also used in critically ill patients who require a breathing tube connected to a ventilator (a machine that moves air in and out of the lungs when a person cannot breathe on their own).
Propofol may be used for other purposes not listed in this medication guide.
Before you receive propofol, tell your doctor if you have epilepsy or other seizure disorder, high triglycerides (fats in the blood), liver disease, or kidney disease.
Your caregivers will monitor your heart function, blood pressure, and breathing while you are under the effects of propofol.Tell your caregivers at once if you have a serious side effect such as seizure, weak or shallow breathing, fast or slow heart rate, or pain, swelling, blisters, or skin changes where the medicine was injected.
Before you receive propofol, tell your doctor about all other medications you use, especially chloral hydrate (Somnote), droperidol (Inapsine), a sedative, or a narcotic pain medication such as fentanyl (Actiq, Duragesic).Propofol can cause severe drowsiness or dizziness, which may last for several hours. You will need someone to drive you home after your surgery or procedure. Do not drive yourself or do anything that requires you to be awake and alert for at least 24 hours after you have been treated with propofol.
If you have certain conditions, you may need a dose adjustment or special tests to safely receive this medication. Before you receive propofol, tell your doctor if you have:
epilepsy or other seizure disorder;
high triglycerides (fats in the blood);
liver disease; or
Propofol is given as an injection through a needle placed into a vein. You will receive this injection in a hospital or surgical setting.
You will relax and fall asleep very quickly after propofol is injected.
Your caregivers will monitor your heart function, blood pressure, and breathing while you are under the effects of propofol.
Since propofol is given by a healthcare professional in a controlled setting, you are not likely to miss a dose.
An overdose of propofol is unlikely to occur since the medication is given by a healthcare professional. Your vital signs will be closely watched while you are under anesthesia to make sure the medication is not causing any harmful effects.
pain, swelling, blisters, or skin changes where the medicine was injected;
weak or shallow breathing; or
fast or slow heart rate.
Less serious side effects may include:
slight burning or stinging around the IV needle;
mild itching or skin rash;
numbness or tingly feeling;
confusion, agitation, anxiety;
muscle pain; or
This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect. You may report side effects to FDA at 1-800-FDA-1088.
Tell your doctor about all other medications you use, especially:
chloral hydrate (Somnote);
a barbiturate such as amobarbital (Amytal), butabarbital (Butisol), mephobarbital (Mebaral), secobarbital (Seconal), or phenobarbital (Solfoton);
diazepam (Valium) or similar medicines such as alprazolam (Xanax), chlordiazepoxide (Librium), clorazepate (Tranxene), estazolam (ProSom), flurazepam (Dalmane), lorazepam (Ativan), midazolam (Versed), temazepam (Restoril), triazolam (Halcion), and others; or
a narcotic medication such as fentanyl (Actiq, Duragesic), hydrocodone (Lortab, Vicodin), hydromorphone (Dilaudid, Palladone), morphine (Kadian, MS Contin, Oramorph, and others), oxycodone (OxyContin), oxymorphone (Numorphan, Opana), and others.
This list is not complete and there may be other drugs that can interact with propofol. Tell your doctor about all your prescription and over-the-counter medications, vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start a new medication without telling your doctor.