Severe and sometimes fatal side effects have occurred with the use of Docetaxel . The risk of these side effects is greater in patients who have abnormal liver function or who receive high doses of Docetaxel . The risk is also greater in certain lung cancer patients who have previously been treated with a platinum-based chemotherapy.
Patients who have certain abnormal liver function tests should usually not use Docetaxel . These patients may be at increased risk of severe side effects, including blood problems (eg, low white blood cell levels, low platelet levels), infection, mouth inflammation, skin toxicity, or death. Patients who have low levels of certain white blood cells (neutrophils) should also not use Docetaxel . Lab tests, including liver function and complete blood cell counts, will be performed while you use Docetaxel .
Severe and sometimes fatal allergic reactions have occurred with the use of Docetaxel . Seek medical care at once if you experience a rash; reddening of the skin; swelling of the mouth, face, or tongue; severe dizziness; or trouble breathing. Patients who have a history of allergic reaction to Docetaxel or to polysorbate 80 should not use Docetaxel .
Severe fluid retention may occur with the use of Docetaxel . Contact your doctor right away if you experience swelling of the hands, ankles, or feet; sudden unusual weight gain; trouble breathing; chest pain or tightness; fast or irregular heartbeat; or stomach swelling.
Treating certain types of breast cancer or non-small cell lung cancer. It may be used alone or with other medicines. Docetaxel is also used along with other medicines to treat certain types of prostate, head and neck, or stomach cancer. It may also be used for other conditions as determined by your doctor.
Docetaxel is an antineoplastic agent. It works by stopping the growth and reproduction of cancer cells in the body.
Contact your doctor or health care provider right away if any of these apply to you.
Some medical conditions may interact with Docetaxel . Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:
Some MEDICINES MAY INTERACT with Docetaxel . Tell your health care provider if you are taking any other medicines, especially any of the following:
This may not be a complete list of all interactions that may occur. Ask your health care provider if Docetaxel may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.
Use Docetaxel as directed by your doctor. Check the label on the medicine for exact dosing instructions.
Ask your health care provider any questions you may have about how to use Docetaxel .
All medicines may cause side effects, but many people have no, or minor side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:
Color changes of the toenails or fingernails; constipation; diarrhea; dizziness; hair loss; increased tear production; loss of appetite; mild pain, swelling, or redness at the injection site; muscle or joint pain; nausea; numbness, tingling, burning, or weakness in the hands, arms, legs, or feet; taste changes; vomiting; weakness or tiredness.Seek medical attention right away if any of these SEVERE side effects occur:
Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); back pain; black or bloody stools; chest pain or tightness; fainting; fast, slow, or irregular heartbeat; fever, chills, or sore throat; flushing; increased or painful urination; mouth sores or inflammation; red, swollen, blistered, or peeling skin; severe or persistent dizziness or headache; severe or persistent nausea, vomiting, diarrhea, or stomach pain; severe or persistent weakness or tiredness; shortness of breath; stomach swelling; sudden unusual weight gain; swelling of the hands, feet, or ankles; swollen lymph glands; trouble swallowing; unusual bruising or bleeding; vision problems; vomit that looks like coffee grounds; warm sensation while you are receiving Docetaxel ; yellowing of the eyes or skin.
This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. You may also report side effects at http://www.fda.gov/medwatch.
Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (http://www.aapcc.org), or emergency room immediately. Symptoms may include burning, numbness, tingling, or loss of feeling in the hands or feet; mouth sores or inflammation; severe weakness or tiredness.Proper storage of Docetaxel :
Docetaxel is usually handled and stored by a health care provider. If you are using Docetaxel at home, store Docetaxel as directed by your pharmacist or health care provider. Keep Docetaxel out of the reach of children and away from pets.
This information is a summary only. It does not contain all information about Docetaxel . If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.