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Drugs reference index «dorzolamide Ophthalmic»

dorzolamide (Ophthalmic route)

dor-ZOLE-a-mide

Commonly used brand name(s):

In the U.S.

  • Trusopt Ocumeter
  • Trusopt Ocumeter Plus

Available Dosage Forms:

  • Solution

Therapeutic Class: Antiglaucoma

Pharmacologic Class: Carbonic Anhydrase Inhibitor

Uses For dorzolamide

Dorzolamide is a carbonic anhydrase inhibitor that is used in the eye. It is used to treat increased pressure in the eye caused by open-angle glaucoma. It is also used to treat a condition called hypertension of the eye.

Dorzolamide is available only with your doctor's prescription.

Before Using dorzolamide

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For dorzolamide, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to dorzolamide or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

dorzolamide has been tested in children and, in effective doses, has not been shown to cause different side effects or problems than it does in adults.

Geriatric

dorzolamide has been tested in a limited number of patients 65 years of age or older and has not been shown to cause different side effects or problems in older people than it does in younger adults.

Pregnancy

Pregnancy CategoryExplanation
All TrimestersCAnimal studies have shown an adverse effect and there are no adequate studies in pregnant women OR no animal studies have been conducted and there are no adequate studies in pregnant women.

Breast Feeding

There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

Interactions with Medicines

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. Tell your healthcare professional if you are taking any other prescription or nonprescription (over-the-counter [OTC]) medicine.

Interactions with Food/Tobacco/Alcohol

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.

Other Medical Problems

The presence of other medical problems may affect the use of dorzolamide. Make sure you tell your doctor if you have any other medical problems, especially:

  • Acute angle-closure glaucoma—Use of ophthalmic dorzolamide in these patients has not been studied. This condition may need other medicine or treatment besides dorzolamide.
  • Kidney disease, severe, or
  • Liver disease—Use of ophthalmic dorzolamide may lead to increased side effects from the medication
  • Kidney stones—Use of ophthalmic dorzolamide may make this condition worse

Proper Use of dorzolamide

To use: First, wash your hands. Tilt the head back and, pressing your finger gently on the skin just beneath the lower eyelid, pull the lower eyelid away from the eye to make a space. Drop the medicine into this space. Let go of the eyelid and gently close the eyes. Do not blink. Keep the eyes closed and apply pressure to the inner corner of the eye with your finger for 1 or 2 minutes to allow the medicine to be absorbed by the eye.

Do not touch or contaminate the tip of the container.

Use dorzolamide only as directed. Do not use more of it and do not use it more often than your doctor ordered. To do so may increase the chance of too much medicine being absorbed into the body and the chance of side effects.

If your doctor ordered two different eye drops to be used together, wait at least 10 minutes between the times you apply the medicines. This will help to keep the second medicine from “washing out” the first one.

Dosing

The dose of dorzolamide will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of dorzolamide. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

  • For ophthalmic dosage form (eye drops):
    • For glaucoma or hypertension of the eye:
      • Adults and teenagers—Use one drop in the eye three times a day.
      • Children—Use and dose must be determined by your doctor.

Missed Dose

If you miss a dose of dorzolamide, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.

Storage

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Precautions While Using dorzolamide

It is important that your doctor check your progress at regular visits. Your doctor may want to do certain tests to see if the medicine is working properly or to see if certain side effects may be occurring without your knowing it.

If itching, redness, swelling, or other signs of eye or eyelid irritation occur, check with your doctor. These signs may mean that you are allergic to ophthalmic dorzolamide.

dorzolamide may cause some people to have blurred vision for a short time. Make sure you know how you react to dorzolamide before you drive, use machines, or do anything else that could be dangerous if you cannot see properly. Also, since blurred vision may be a sign of a side effect that needs medical attention, check with your doctor if it continues.

Ophthalmic dorzolamide may cause your eyes to become more sensitive to light than they are normally. Wearing sunglasses and avoiding too much exposure to bright light may help lessen the discomfort. If the discomfort continues, check with your doctor.

dorzolamide Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor as soon as possible if any of the following side effects occur:

More common
  • Itching, redness, swelling, or other sign of eye or eyelid irritation
Less common
  • Burning, dry or itching eyes
  • discharge from the eye
  • excessive tearing
  • redness, pain, or swelling of eye, eyelid, or inner lining of eyelid
Rare
  • Blurred vision
  • eye pain
  • skin rash
  • symptoms of kidney stone (blood in urine, nausea or vomiting, or pain in side, back, or abdomen)
  • tearing
Incidence not known- occurred during clinical practice
  • Change in vision
  • cough
  • difficult or labored breathing
  • flashes of light
  • floaters in vision
  • hives or welts
  • itching skin
  • large, hive-like swelling on face, eyelids, lips, tongue, throat, hands, legs, feet, sex organs
  • noisy breathing
  • redness of skin
  • shortness of breath
  • tightness in chest
  • wheezing

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common
  • Bitter taste
  • burning, stinging, or discomfort when medicine is applied
  • feeling of something in eye
  • sensitivity of eyes to light
Less common
  • Dryness of eyes
  • eyelid reactions
  • headache
  • nausea
  • unusual tiredness or weakness
Incidence not known- occurred during clinical practice
  • Blistering, burning, crusting, dryness, flaking of skin
  • bloody nose
  • burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings
  • change in distance vision
  • difficulty in focusing eyes
  • dizziness
  • dry mouth
  • eyelid crusting
  • scaling of skin
  • severe redness, soreness, swelling of skin

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

The information contained in the Thomson Healthcare (Micromedex) products as delivered by Drugs.com is intended as an educational aid only. It is not intended as medical advice for individual conditions or treatment. It is not a substitute for a medical exam, nor does it replace the need for services provided by medical professionals. Talk to your doctor, nurse or pharmacist before taking any prescription or over the counter drugs (including any herbal medicines or supplements) or following any treatment or regimen. Only your doctor, nurse, or pharmacist can provide you with advice on what is safe and effective for you.

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  • dorzolamide ophthalmic Concise Consumer Information (Cerner Multum)
  • Trusopt Prescribing Information (FDA)
  • Trusopt Drops MedFacts Consumer Leaflet (Wolters Kluwer)

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