Doxil is for intravenous (IV) use only. If Doxil accidentally leaks into surrounding tissue, the skin or muscle may be severely damaged. Notify your doctor immediately if redness, pain, or swelling at or around the injection site occur. Doxil may cause heart problems (eg, heart failure) or bone marrow suppression. Notify your doctor immediately if you develop an irregular heartbeat, trouble breathing, swelling of the hands or feet, easy bruising or bleeding, a dry cough, or signs of an infection (eg, fever, unusual tiredness, persistent sore throat). Heart problems may occur during therapy or sometimes months to years after receiving Doxil . The risk of developing heart problems varies depending on your dose and condition. The risk may be increased if you have a history of radiation therapy or if you are using cyclophosphamide. Tell your doctor if you have liver problems because your dose will have to be decreased. Your doctor will closely monitor you while you are using Doxil .
Treating advanced ovarian cancer and AIDS-related Kaposi sarcoma in certain patients. It is also used with another medicine to treat a type of bone marrow cancer (multiple myeloma) in certain patients.
Doxil is an antineoplastic antibiotic. It works by killing cancer cells.
Contact your doctor or health care provider right away if any of these apply to you.
Some medical conditions may interact with Doxil . Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:
Some MEDICINES MAY INTERACT with Doxil . Tell your health care provider if you are taking any other medicines, especially any of the following:
This may not be a complete list of all interactions that may occur. Ask your health care provider if Doxil may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.
Use Doxil as directed by your doctor. Check the label on the medicine for exact dosing instructions.
Ask your health care provider any questions you may have about how to use Doxil .
All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:
Diarrhea; hair loss; loss of appetite; nausea; pain, redness, or swelling at the injection site; red-colored urine 1 to 2 days after receiving Doxil ; tiredness; vomiting; weakness.Seek medical attention right away if any of these SEVERE side effects occur:
Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); back pain; bleeding or bruising; chest pain; cough; dizziness; fainting; flushing; hand-foot syndrome (tingling, burning, redness, swelling, flaking, small blisters or small sores on the palms of hands or sores of feet); headache; irregular or fast heartbeat; loose or bloody stools; rectal bleeding or irritation; serious infection (fever, chills, persistent sore throat); shortness of breath; sores in the mouth or on the lips; sudden weight gain; swelling of the face or ankles; tightness in the chest and throat; unusual tiredness.
This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. You may also report side effects at http://www.fda.gov/medwatch.
Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (http://www.aapcc.org), or emergency room immediately. Symptoms may include inflammation of the mouth.Proper storage of Doxil :
Doxil is usually handled and stored by a health care provider. If you are using Doxil at home, store Doxil as directed by your pharmacist or health care provider. Keep Doxil out of the reach of children and away from pets.
This information is a summary only. It does not contain all information about Doxil . If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.