Doxycycline (DOX-i-SYE-kleen)Brand Name:
Doxycycline are used for:
Treating periodontitis, a dental disease that attacks the gum, bone, and around the teeth.
Doxycycline are a tetracycline. It works to treat periodontitis by decreasing the activity of a certain enzyme (collagenase).
Do NOT use Doxycycline if:
- you are allergic to any ingredient in Doxycycline or to another tetracycline (eg, minocycline)
- you are taking acitretin, isotretinoin, methotrexate, or a blood thinner (eg, warfarin)
- you have recently received or will be receiving a live oral typhoid vaccine
Contact your doctor or health care provider right away if any of these apply to you.
Before using Doxycycline:
Some medical conditions may interact with Doxycycline. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:
- if you are pregnant, planning to become pregnant, or are breast-feeding
- if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
- if you have allergies to medicines, foods, or other substances
- if you have diarrhea, a stomach infection, a history of lupus, or the blood disease porphyria
- if you have a history of oral yeast infections
Some MEDICINES MAY INTERACT with Doxycycline. Tell your health care provider if you are taking any other medicines, especially any of the following:
- Barbiturates (eg, phenobarbital), carbamazepine, cimetidine, colestipol, hydantoins (eg, phenytoin), or rifampin because they may decrease Doxycycline's effectiveness
- Acitretin, digoxin, insulin,isotretinoin, methotrexate, methoxyflurane,blood thinners (eg, warfarin), or theophylline because the risk of their side effects may be increased by Doxycycline
- Live oral typhoid vaccine, hormonal birth control (eg, birth control pills), or penicillins (eg, amoxicillin) because their effectiveness may be decreased by Doxycycline
This may not be a complete list of all interactions that may occur. Ask your health care provider if Doxycycline may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.
How to use Doxycycline:
Use Doxycycline as directed by your doctor. Check the label on the medicine for exact dosing instructions.
- Take Doxycycline by mouth on an empty stomach at least 1 hour before or 2 hours after eating.
- Do not take an antacid that has aluminum, calcium, or magnesium in it; bismuth subsalicylate; iron; zinc; or multivitamins with minerals within 2 hours before or 2 hours after you take Doxycycline.
- Do not eat or drink dairy products within 1 hour before or 2 hours after you take Doxycycline.
- To clear up your infection completely, take Doxycycline for the full course of treatment. Keep taking it even if you feel better in a few days.
- Drink plenty of nondairy fluid with Doxycycline to wash it down and avoid the risk of sore throat.
- Take Doxycycline twice daily (every 12 hours), preferably in the morning and evening.
- Continue to take Doxycycline even if you feel well. Do not miss any doses.
- If you miss a dose of Doxycycline, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.
Ask your health care provider any questions you may have about how to use Doxycycline.
Important safety information:
- Hormonal birth control (eg, birth control pills) may not work as well while you are using Doxycycline. To prevent pregnancy, use an extra form of birth control (eg, condoms).
- Mild diarrhea is common with this type of medicine. However, a more serious form of diarrhea (pseudomembranous colitis) may rarely occur. This may develop while you use Doxycycline or within several months after you stop using it. Contact your doctor right away if stomach pain or cramps, severe diarrhea, or bloody stools occur. Do not treat diarrhea without first checking with your doctor.
- Long-term or repeated use of Doxycycline may cause a second infection. Tell your doctor if signs of a second infection occur. Your medicine may need to be changed to treat this.
- Doxycycline may cause you to become sunburned more easily. Avoid the sun, sunlamps, or tanning booths until you know how you react to Doxycycline. Use a sunscreen or wear protective clothing if you must be outside for more than a short time.
- Tell your doctor or dentist that you take Doxycycline before you receive any medical or dental care, emergency care, or surgery.
- Doxycycline may interfere with certain lab tests. Be sure your doctor and lab personnel know you are taking Doxycycline.
- Lab tests, including liver function, kidney function, and complete blood counts, may be performed while you use Doxycycline. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.
- Doxycycline should not be used in CHILDREN younger than 8 years old; permanent yellow-gray-brown tooth discoloration may occur.
- PREGNANCY and BREAST-FEEDING: Doxycycline has been shown to cause harm to the fetus. If you think you may be pregnant, contact your doctor. You will need to discuss the benefits and risks of using Doxycycline while you are pregnant. Doxycycline are found in breast milk. Do not breast-feed while taking Doxycycline.
Possible side effects of Doxycycline:
All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:
Diarrhea; nausea; sensitivity to sunlight; stomach upset.Seek medical attention right away if any of these SEVERE side effects occur:
Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue; unusual hoarseness); bloody stools; chest pain; dark urine; decreased urination; fever, chills, or sore throat; moderate to severe sunburn; severe diarrhea; severe or persistent headache; stomach pain or cramps; throat irritation; trouble swallowing; unusual bruising or bleeding; unusual joint pain; unusual tiredness; vaginal irritation or discharge; vision changes; yellowing of the skin or eyes.
This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. You may also report side effects at http://www.fda.gov/medwatch.
If OVERDOSE is suspected:
Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (http://www.aapcc.org), or emergency room immediately.Proper storage of Doxycycline:
Store Doxycycline at room temperature, between 59 and 86 degrees F (15 and 30 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep Doxycycline out of the reach of children and away from pets.
- If you have any questions about Doxycycline, please talk with your doctor, pharmacist, or other health care provider.
- Doxycycline are to be used only by the patient for whom it is prescribed. Do not share it with other people.
- If your symptoms do not improve or if they become worse, check with your doctor.
This information is a summary only. It does not contain all information about Doxycycline. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.
- Doxycycline Prescribing Information (FDA)
- Doxycycline Professional Patient Advice (Wolters Kluwer)
- Doxycycline Detailed Consumer Information (PDR)
- doxycycline Advanced Consumer (Micromedex) - Includes Dosage Information
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