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Drugs reference index «eletriptan»

eletriptan


eletriptan (Oral route)

el-e-TRIP-tan

Commonly used brand name(s):

In the U.S.

  • Relpax

Available Dosage Forms:

  • Tablet

Therapeutic Class: Antimigraine

Pharmacologic Class: Serotonin Receptor Agonist, 5-HT1

Uses For eletriptan

Eletriptan is used to treat severe migraine headaches. Many people find that their headaches go away completely after they take eletriptan. Other people find that their headaches are much less painful, and that they are able to go back to their normal activities even though their headaches are not completely gone. Eletriptan often relieves other symptoms that occur together with a migraine headache, such as nausea, vomiting, sensitivity to light, and sensitivity to sound.

Eletriptan is not an ordinary pain reliever. It will not relieve any kind of pain other than migraine headaches. eletriptan is usually used for people whose headaches are not relieved by acetaminophen, aspirin, or other pain relievers.

Eletriptan has caused serious side effects in some people, especially people who have heart or blood vessel disease. Be sure that you discuss with your doctor the risks of using eletriptan as well as the good that it can do.

eletriptan is available only with your doctor's prescription.

Before Using eletriptan

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For eletriptan, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to eletriptan or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Studies on eletriptan have been done only on a small number of adolescents (11 to 17 years of age). However, eletriptan is not recommended for use in patients younger than 18 years of age.

Geriatric

Many medicines have not been studied specifically in older people. Therefore, it may not be known whether they work exactly the same way they do in younger adults. However, eletriptan has been shown to remain in the body longer in elderly patients. It has also been shown to increase blood pressure.

Pregnancy

Pregnancy CategoryExplanation
All TrimestersCAnimal studies have shown an adverse effect and there are no adequate studies in pregnant women OR no animal studies have been conducted and there are no adequate studies in pregnant women.

Breast Feeding

There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

Interactions with Medicines

Using eletriptan with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.

  • Frovatriptan
  • Linezolid

Using eletriptan with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

  • Amiodarone
  • Citalopram
  • Desvenlafaxine
  • Dihydroergotamine
  • Duloxetine
  • Ergoloid Mesylates
  • Ergonovine
  • Ergotamine
  • Escitalopram
  • Fluoxetine
  • Fluvoxamine
  • Methylergonovine
  • Milnacipran
  • Paroxetine
  • Reboxetine
  • Sertraline
  • Sibutramine
  • St John's Wort
  • Tapentadol

Using eletriptan with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

  • Ketoconazole

Interactions with Food/Tobacco/Alcohol

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.

Other Medical Problems

The presence of other medical problems may affect the use of eletriptan. Make sure you tell your doctor if you have any other medical problems, especially:

  • Basilar migraine or
  • Cerebrovascular syndrome, such as
  • Stroke or
  • Transient ischemic attack (TIA) or
  • Coronary artery disease, such as
  • Angina (chest pain) or
  • Decreased blood flow to your heart or
  • Heart attack, history of, or
  • Other heart conditions or
  • Hemiplegic migraine or
  • High blood pressure, not treated or
  • Liver problems, severe or
  • Peripheral vascular disease, such as
  • Bowel disease or
  • Raynaud's syndrome—Eletriptan should not be used if you have any of these conditions.
  • Cerebrovascular event—Eletriptan should be used with caution in patients who have an increased risk of bleeding in the brain, stroke, or transient ischemic attack (TIA).
  • Coronary artery disease, predisposition to—Eletriptan and similar medicines may cause serious heart problems, especially if you have a predisposition for heart problems.
  • High blood pressure, treated—Eletriptan may cause high blood pressure in patients already being treated for high blood pressure.
  • Kidney problems—Eletriptan may cause increased blood pressure in patients who have kidney problems.
  • Liver problems, mild or moderate—This could cause higher blood levels of eletriptan.

Proper Use of eletriptan

Do not use eletriptan for a headache that is different from your usual migraines . Instead, check with your doctor.

To relieve your migraine as soon as possible, use eletriptan as soon as the headache pain begins.

You may get additional benefit from eletriptan if you lie down in a quiet, dark room after taking eletriptan.

Ask your doctor ahead of time about any other medicine you may take if eletriptan does not work. After you take the other medicine, check with your doctor as soon as possible.

If you feel much better after a dose of eletriptan, but your headache comes back or gets worse after 2 or more hours, you may use one additional dose of eletriptan. Do not take a second tablet if the first did not help your headache at all. However, use eletriptan only as directed by your doctor. Do not use more of it, and do not use it more often than directed.

Dosing

The dose of eletriptan will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of eletriptan. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

  • For oral dosage form (tablets):
    • For migraine headaches:
      • Adults—20 milligrams (mg) or 40 mg as a single dose. If the migraine comes back after being relieved, another dose be taken two hours or more after the first dose. Do not take more than 2 doses in any twenty-four-hour period
      • Children—Use and dose must be determined by your doctor.

Storage

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Precautions While Using eletriptan

Drinking alcoholic beverages may make headaches worse or cause new headaches to occur. People who suffer from severe headaches should probably avoid alcoholic beverages.

Call your doctor if your usual dose of eletriptan does not relieve three consecutive headaches, or the frequency or severity of headaches increases.

Call your doctor right away if you have severe chest pains or shortness of breath.

eletriptan may cause some people to become drowsy, dizzy, or less alert than they are normally. Make sure you know how you react to eletriptan before you drive, use machines, or do anything else that could be dangerous if you are dizzy or are not alert.

eletriptan Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

Less common
  • Chest pain or tightness
  • difficulty swallowing

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More Common
  • Dizziness
  • lack or loss of strength
  • nausea
  • sleepiness or unusual drowsiness
Less common
  • Acid or sour stomach
  • belching
  • burning, crawling, itching, numbness, prickling, “pins and needles”, or tingling feelings
  • dry mouth
  • feeling of warmth
  • headache
  • heartburn
  • indigestion
  • redness of the face, neck, arms, and occasionally upper chest
  • stomach soreness or discomfort
  • stomach upset or pain

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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  • Eletriptan MedFacts Consumer Leaflet (Wolters Kluwer)
  • Relpax Prescribing Information (FDA)
  • Relpax Detailed Consumer Information (PDR)
  • Relpax Consumer Overview

See Also...

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