Generic name: HydrochlorothiazideBrand names: Esidrix, HydroDIURIL
HydroDIURIL is used in the treatment of high blood pressure and other conditions that require the elimination of excess fluid (water) from the body. These conditions include congestive heart failure, cirrhosis of the liver, corticosteroid and estrogen therapy, and kidney disorders. When used for high blood pressure, HydroDIURIL can be used alone or with other high blood pressure medications. HydroDIURIL contains a form of thiazide, a diuretic that prompts your body to produce and eliminate more urine, which helps lower blood pressure.
If you have high blood pressure, you must take HydroDIURIL regularly for it to be effective. Since blood pressure declines gradually, it may be several weeks before you get the full benefit of HydroDIURIL; and you must continue taking it even if you are feeling well. HydroDIURIL does not cure high blood pressure; it merely keeps it under control.
Take HydroDIURIL exactly as prescribed by your doctor.
Side effects cannot be anticipated. If any develop or change in intensity, inform your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking HydroDIURIL.
If you are unable to urinate, you should not take Esidrix.
If you are sensitive to or have ever had an allergic reaction to HydroDIURIL or similar drugs, or if you are sensitive to sulfa or other sulfonamide-derived drugs, you should not take Esidrix.
Diuretics can cause your body to lose too much potassium. Signs of an excessively low potassium level include muscle weakness and rapid or irregular heartbeat. To boost your potassium level, your doctor may recommend eating potassium-rich foods or taking a potassium supplement.
If you are taking HydroDIURIL, your kidney function should be given a complete assessment, and should continue to be monitored.
If you have liver disease, diabetes, gout, or lupus erythematosus (a form of rheumatism), HydroDIURIL should be used with caution.
If you have bronchial asthma or a history of allergies, you may be at greater risk for an allergic reaction to Esidrix.
Dehydration, excessive sweating, severe diarrhea or vomiting could deplete your body's fluids and cause your blood pressure to become too low. Be careful when exercising and in hot weather.
HydroDIURIL may increase the effects of alcohol. Do not drink alcohol while taking Esidrix.
If HydroDIURIL is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your doctor before combining HydroDIURIL with the following:Barbiturates such as phenobarbitalCholestyramineColestipolCorticosteroids such as prednisone and ACTHDigoxinDrugs to treat diabetes such as insulin or glyburideLithiumNarcotics such as oxycodoneNonsteroidal anti-inflammatory drugs such as naproxenNorepinephrineOther high blood pressure medications such as methyldopaSkeletal muscle relaxants, such as tubocurarine
The effects of HydroDIURIL during pregnancy have not been adequately studied. If you are pregnant or plan to become pregnant, inform your doctor immediately. HydroDIURIL appears in breast milk and could affect a nursing infant. If Esidrix is essential to your health, your doctor may advise you to discontinue breastfeeding until your treatment is finished.
Dosage should be adjusted to each individual's needs. The smallest dose that is effective should be used.
The usual dose is 25 milligrams to 100 milligrams per day. Your doctor may tell you to take the drug in a single dose or to divide the total amount into more than one dose. Your doctor may put you on a day on, day off schedule or some other alternate day schedule to suit your needs.
High Blood Pressure
The usual dose is 25 milligrams as a single dose. Your doctor may increase the dose to 50 milligrams, as a single dose or divided into 2 doses. Dosages should be adjusted when used with other high blood pressure medications.
Dosages for children should be adjusted according to weight, generally 0.5 to 1 milligram per pound of body weight in 1 or 2 doses per day. Infants under 2 years should not receive more than 37.5 milligrams per day, and children aged 2 to 12 should not get more than 100 milligrams a day. Infants under 6 months may need 1.5 milligrams per pound per day in 2 doses.
Under 2 years
Based on age and body weight, the daily dosage is 12.5 milligrams to 37.5 milligrams per day.
2 to 12 years
The daily dosage, based on body weight, is 37.5 milligrams to 100 milligrams.
HydroDIURIL tablets come in strengths of 25, 50 and 100 milligrams.
Any medication taken in excess can cause symptoms of overdose. If you suspect an overdose, seek medical attention immediately.