Serious and sometimes fatal allergic reactions have occurred with use of Aldurazyme . Tell your doctor right away if you develop rash; itching; fast or difficult breathing; chest tightness; severe dizziness; swelling of hands, face, lips, eyes, throat, or tongue; difficulty swallowing; or hoarseness.
Tell your doctor if you have lung or breathing problems. You may be at risk for severe worsening of your breathing problems if you experience an allergic reaction to Aldurazyme .
Treating patients with Hurler and Hurler-Scheie forms of mucopolysaccharidosis I (MPS I), and patients with Scheie form who have moderate to severe symptoms.
Aldurazyme is a glycoprotein. It works by providing the enzyme alpha-L-iduronidase to the body.
Contact your doctor or health care provider right away if this applies to you.
Some medical conditions may interact with Aldurazyme . Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:
Some MEDICINES MAY INTERACT with Aldurazyme . However, no specific interactions with Aldurazyme are known at this time.
Ask your health care provider if Aldurazyme may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.
Use Aldurazyme as directed by your doctor. Check the label on the medicine for exact dosing instructions.
Ask your health care provider any questions you may have about how to use Aldurazyme .
All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:
Flushing; headache; mild redness, stinging, or pain at the injection site.Seek medical attention right away if any of these SEVERE side effects occur:
Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue; unusual hoarseness); chest pain; cough; diarrhea; dizziness; fast or slow heartbeat; fever, chills, or sore throat; joint pain; nausea; numbness or tingling of the skin; rapid breathing; severe headache; stomach pain; unusual bruising or bleeding; unusual swelling; vision changes; vomiting.
This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. You may also report side effects at http://www.fda.gov/medwatch.
Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (http://www.aapcc.org), or emergency room immediately.Proper storage of Aldurazyme :
Aldurazyme is usually handled and stored by a health care provider. If you are using Aldurazyme at home, store Aldurazyme as directed by your pharmacist or health care provider.
This information is a summary only. It does not contain all information about Aldurazyme . If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.