Serious infections, blood disorders, and infusion reactions have occurred from the use of Alemtuzumab . You will be closely monitored during the infusion and it may be necessary to stop treatment if an infusion reaction occurs. Notify your doctor immediately if you experience rigid muscles, fever, shortness of breath, tightness in the throat, fainting, chest pain, chills, or rash.
Treating B cell chronic lymphocytic leukemia (CLL). It may also be used for other conditions as determined by your doctor.
Alemtuzumab is a monoclonal antibody. It works by recognizing certain proteins that are found on the surface of certain types of cancer cells. Once the proteins are recognized, the body's immune system can kill the cancer cells.
Contact your doctor or health care provider right away if any of these apply to you.
Some medical conditions may interact with Alemtuzumab . Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:
Some MEDICINES MAY INTERACT with Alemtuzumab . However, no specific interactions with Alemtuzumab are known at this time.
Ask your health care provider if Alemtuzumab may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.
Use Alemtuzumab as directed by your doctor. Check the label on the medicine for exact dosing instructions.
Ask your health care provider any questions you may have about how to use Alemtuzumab .
All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:
Abnormal skin sensations; back pain; bone pain; constipation; cough; depression; dizziness; general body discomfort; increased sweating; indigestion; loss of appetite; muscle pain; nosebleed; runny nose; sensation of temperature change; sleeplessness; stomach pain; tiredness; tremor; weakness; weight loss.Seek medical attention right away if any of these SEVERE side effects occur:
Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); black, tarry stools; blood in urine; bronchitis; chest pain; decreased hearing; diarrhea; extreme tiredness; fainting; fast or irregular heartbeat; fever; headache; hoarseness; itching; lightheadedness upon sitting or standing up; nausea; painful or difficult urination; pale skin; pneumonia; rapid weight gain; rigid muscles; shortness of breath; sores or ulcers on the lips or mouth; sudden sweating; swelling of the legs or feet; unusual bruising or bleeding; vomiting.
This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. You may also report side effects at http://www.fda.gov/medwatch.
Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (http://www.aapcc.org), or emergency room immediately. Symptoms may include chest tightness; cough; difficulty breathing; inability to urinate; shortness of breath.Proper storage of Alemtuzumab :
Store Alemtuzumab in the refrigerator, between 36 and 46 degrees F (2 and 8 degrees C). Do not freeze. Discard if vial has been frozen. Keep Alemtuzumab out of the reach of children and away from pets.
This information is a summary only. It does not contain all information about Alemtuzumab . If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.