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Drugs reference index «Factive»

Factive
Factive


Factive

Generic Name: gemifloxacin (JEM i FLOX a sin)Brand Names: Factive

What is Factive (gemifloxacin)?

Gemifloxacin is an antibiotic in a group of drugs called fluoroquinolones (flor-o-KWIN-o-lones). Gemifloxacin fights bacteria in the body.

Gemifloxacin is used to treat different types of bacterial infections.

Gemifloxacin may also be used for other purposes not listed in this medication guide.

What is the most important information I should know about moxifloxacin?

You should not use this medication if you are allergic to gemifloxacin or similar antibiotics such as ciprofloxacin (Cipro), levofloxacin (Levaquin), moxifloxacin (Avelox), ofloxacin (Floxin), norfloxacin (Noroxin), lomefloxacin (Maxaquin), and others.

Before taking gemifloxacin, tell your doctor if you have kidney disease, joint problems, a history of seizures, low levels of potassium or magnesium in your blood, a nerve disorder or history of circulation problems, or a personal or family history of "Long QT syndrome."

Avoid taking antacids, vitamin or mineral supplements, sucralfate (Carafate), or didanosine (Videx) powder or chewable tablets within 3 hours before or 2 hours after you take gemifloxacin. These other medicines can make gemifloxacin much less effective when taken at the same time.

Taking gemifloxacin can make your skin more sensitive to sunlight. Avoid exposure to sunlight, sun lamps, or tanning beds.

Gemifloxacin may cause swelling or tearing of a tendon (the fiber that connects bones to muscles in the body), especially in the Achilles' tendon of the heel. These effects may be more likely to occur if you are over 60, if you take an oral steroid medication, or if you have had a kidney, heart, or lung transplant. Stop taking gemifloxacin and call your doctor at once if you have sudden pain, swelling, tenderness, stiffness, or movement problems in any of your joints. Rest the joint until you receive medical care or instructions. Do not share this medication with another person (especially a child), even if they have the same symptoms you do.What should I discuss with my healthcare provider before taking Factive (gemifloxacin)?Do not use this medication if you are allergic to gemifloxacin or similar medications such as ciprofloxacin (Cipro), levofloxacin (Levaquin), ofloxacin (Floxin), moxifloxacin (Avelox), norfloxacin (Noroxin), lomefloxacin (Maxaquin), and others.

Before taking gemifloxacin, tell your doctor if you have a heart rhythm disorder, especially if you are being treated with one of these medications: quinidine (Cardioquin, Quinidex, Quinaglute), disopyramide (Norpace), bretylium (Bretylol), procainamide (Pronestyl, Procan SR), amiodarone (Cordarone, Pacerone), or sotalol (Betapace).

If you have certain conditions, you may need a dose adjustment or special tests to safely use this medication. Before you take gemifloxacin, tell your doctor if you have:

  • a history of allergic reaction to an antibiotic;
  • joint problems;

  • kidney disease;
  • epilepsy or a history of seizures;

  • low blood levels of potassium (hypokalemia) or magnesium (hypomagnesemia);

  • a nerve disorder or history of circulation problems; or

  • a personal or family history of "Long QT syndrome."

FDA pregnancy category C: It is not known whether gemifloxacin is harmful to an unborn baby. Do not use gemifloxacin without telling your doctor if you are pregnant. Tell your doctor if you become pregnant during treatment. Gemifloxacin may pass into breast milk and could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby. Gemifloxacin may cause swelling or tearing of a tendon (the fiber that connects bones to muscles in the body), especially in the Achilles' tendon of the heel. These effects may be more likely to occur if you are over 60, if you take an oral steroid medication, or if you have had a kidney, heart, or lung transplant. Stop taking gemifloxacin and call your doctor at once if you have sudden pain, swelling, tenderness, stiffness, or movement problems in any of your joints. Rest the joint until you receive medical care or instructions. Do not share this medication with another person (especially a child), even if they have the same symptoms you do.

How should I take Factive (gemifloxacin)?

Take gemifloxacin exactly as it was prescribed for you. Do not take it in larger doses or for longer than recommended by your doctor. Follow the directions on your prescription label.

Take gemifloxacin with a full glass of water (8 ounces). Drink several extra glasses of fluid each day while you are taking gemifloxacin.

Gemifloxacin may be taken with or without food, but take it at the same time each day.

Take this medication for as many days as it has been prescribed for you even if you begin to feel better. Your symptoms may get better before the infection is completely treated. Gemifloxacin will not treat a viral infection such as the common cold or flu. Store gemifloxacin at room temperature away from moisture, heat, and light.

See also: Factive dosage in more detail

What happens if I miss a dose?

Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and take the medicine at the next regularly scheduled time. Do not take extra medicine to make up the missed dose.

What happens if I overdose?

Seek emergency medical attention if you think you have used too much of this medicine.

Overdose symptoms may include weakness, chills, tremors, and seizure (convulsions).

What should I avoid while taking Factive (gemifloxacin)?

You may be taking certain other medicines that should not be taken at the same time as gemifloxacin. Avoid taking the following medicines within 3 hours before or 2 hours after you take gemifloxacin. These other medicines can make gemifloxacin much less effective when taken at the same time:
  • antacids that contain magnesium or aluminum (such as Maalox, Mylanta, or Rolaids);

  • the ulcer medicine sucralfate (Carafate);

  • didanosine (Videx) powder or chewable tablets; or

  • vitamin or mineral supplements that contain iron or zinc.

Avoid exposure to sunlight, sunlamps, or tanning beds. Gemifloxacin can make your skin more sensitive to sunlight, and a sunburn may result. Wear protective clothing and use a sunscreen (SPF-15 or higher) if you must be out in the sun. Call your doctor if you have severe burning, redness, itching, rash, or swelling after being in the sun.

Antibiotic medicines can cause diarrhea, which may be a sign of a new infection. If you have diarrhea that is watery or has blood in it, call your doctor. Do not use any medicine to stop the diarrhea unless your doctor has told you to.

Gemifloxacin can cause side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert.

Factive (gemifloxacin) side effects

Stop using gemifloxacin and get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Stop using gemifloxacin and call your doctor at once if you have any of these serious side effects:
  • dizziness, fainting, fast or pounding heartbeat;

  • sudden pain, snapping or popping sound, bruising, loss of movement, or swelling near your joints (especially in your arm or ankle);

  • diarrhea that is watery or bloody;

  • confusion, hallucinations, depression, unusual thoughts or behavior;

  • seizure (convulsions);

  • pale or yellowed skin, dark colored urine, fever, weakness;

  • upper stomach pain, loss of appetite, clay-colored stools, jaundice (yellowing of the skin or eyes);

  • urinating less than usual or not at all;

  • easy bruising or bleeding;

  • numbness, burning, tingling, or unusual pain anywhere in your body;

  • fever, sore throat, and headache with a severe blistering, peeling, and red skin rash; or

  • the first sign of any skin rash, no matter how mild.

Less serious side effects may include:

  • nausea, vomiting;

  • dizziness or drowsiness;

  • blurred vision;

  • muscle pain;

  • feeling nervous, anxious, or restless; or

  • sleep problems (insomnia or nightmares).

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect Factive (gemifloxacin)?

Before taking gemifloxacin, tell your doctor if you are taking any of the following drugs:

  • probenecid (Benemid, Probalan);

  • a blood thinner such as warfarin (Coumadin);

  • a diuretic (water pill);

  • an antibiotic such as clarithromycin (Biaxin), erythromycin (E.E.S., EryPed, Ery-Tab, Erythrocin), or pentamidine (NebuPent, Pentam);

  • an antidepressant such as amitriptylline (Elavil, Vanatrip), clomipramine (Anafranil), or desipramine (Norpramin);

  • anti-malaria medications such as chloroquine (Arelan), mefloquine (Lariam), or halofantrine (Halfan);

  • medicine to prevent or treat nausea and vomiting, such as dolasetron (Anzemet) or ondansetron (Zofran);

  • medicines to treat psychiatric disorders, such as chlorpromazine (Thorazine), clozapine (FazaClo, Clozaril), haloperidol (Haldol), pimozide (Orap), thioridazine (Mellaril), or ziprasidone (Geodon);

  • migraine headache medicine such as sumatriptan (Imitrex) or zolmitriptan (Zomig);

  • narcotic medication such as levomethadyl (Orlaam), or methadone (Dolophine, Methadose);

  • a nonsteroidal anti-inflammatory drug (NSAID) such as ibuprofen (Motrin, Advil, Nuprin, others), etodolac (Lodine), diclofenac (Cataflam, Voltaren), indomethacin (Indocin), naproxen (Aleve, Naprosyn, Anaprox), piroxicam (Feldene), and others; or

  • an oral steroid medication such as dexamethasone (Decadron, Dexpak), prednisolone (Orapred), prednisone (Meticorten, Sterapred), and others.

This list is not complete and there may be other drugs that can interact with gemifloxacin. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.

Where can I get more information?

  • Your pharmacist can provide more information about gemifloxacin.
  • Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medicine only for the indication prescribed.
  • Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.
Copyright 1996-2006 Cerner Multum, Inc. Version: 2.03. Revision Date: 4/12/2009 4:45:05 PM.
  • Factive Prescribing Information (FDA)
  • Factive Detailed Consumer Information (PDR)
  • Factive Advanced Consumer (Micromedex) - Includes Dosage Information
  • Factive MedFacts Consumer Leaflet (Wolters Kluwer)

See Also...

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