Generic Name: alfuzosin (al FUE zoe sin)Brand Names: Uroxatral
Alfuzosin is in a group of drugs called alpha-adrenergic blockers. Alfuzosin helps relax the muscles in the prostate and bladder neck, making it easier to urinate.
Alfuzosin is used to treat benign prostatic hyperplasia (enlarged prostate).
Alfuzosin may also be used for other purposes not listed in this medication guide.
Alfuzosin can affect the pupils of your eyes during cataract surgery. If you have cataract surgery during your treatment with alfuzosin, tell the surgeon ahead of time that you are taking this medication. Do not stop using alfuzosin before surgery unless your surgeon tells you to.
severe liver disease; or
if you are also using an antifungal medication such as ketoconazole (Nizoral), itraconazole (Sporanox), or ritonavir (Norvir).
If you have any of these other conditions, you may need a dose adjustment or special tests to safely take alfuzosin:
a personal or family history of Long QT syndrome;
angina (chest pain);
coronary artery disease (such as arteriosclerosis);
low blood pressure;
a history of an allergic reaction to alfuzosin;
if you are taking another alpha-blocker such as terazosin (Hytrin), prazosin (Minipress), doxazosin (Cardura), or guanadrel (Hylorel) for high blood pressure or prostate problems;
if you are taking certain medicines to treat HIV or AIDS.
Take this medication exactly as it was prescribed for you. Do not take the medication in larger amounts, or take it for longer than recommended by your doctor. Follow the directions on your prescription label.Take each dose with a full glass of water. Alfuzosin should be taken just after eating food. Take alfuzosin after the same meal each day. Do not take it on an empty stomach. Do not crush, chew, or break an extended-release tablet. Swallow the pill whole. It is specially made to release medicine slowly in the body. Breaking or crushing the pill would cause too much of the drug to be released at one time.
It is important to use alfuzosin regularly to get the most benefit. Get your prescription refilled before you run out of medicine completely.
To be sure this medication is helping your condition, your blood will need to be tested on a regular basis. Do not miss any scheduled visits to your doctor.
Alfuzosin can affect the pupils of your eyes during cataract surgery. If you have cataract surgery during your treatment with alfuzosin, tell the surgeon ahead of time that you are taking this medication. Do not stop using alfuzosin before surgery unless your surgeon tells you to.Store alfuzosin at room temperature away from moisture, heat, and light.
See also: Alfuzosin dosage in more detail
Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and take the medicine at the next regularly scheduled time. Do not take extra medicine to make up the missed dose.
Overdose symptoms may include weakness, dizziness, a fast but weak pulse, cold or clammy skin, and feeling light-headed or fainting.
Avoid getting up too fast from a sitting or lying position, or you may feel dizzy. Get up slowly and steady yourself to prevent a fall.
new or worsening chest pain;
nausea, stomach pain, low fever, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes);
feeling like you might pass out; or
penis erection that is painful or lasts 4 hours or longer.
Less serious side effects may include:
dizziness or drowsiness;
headache, tired feeling;
warmth, redness, or tingly feeling under your skin;
mild stomach pain, diarrhea, constipation; or
sore throat, cough, runny or stuffy nose.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Usual Adult Dose for Benign Prostatic Hyperplasia:
10 mg orally once a day immediately after the same meal each day.
Before taking alfuzosin, tell your doctor if you are taking any other medications to treat high blood pressure or prostate problems.
Tell your doctor about all other medications you use, especially:
diclofenac (Arthrotec, Cataflam, Voltaren, Flector Patch, Solareze);
diltiazem (Cardizem CD, Cartia XT, Tiazac);
isoniazid (for treating tuberculosis);
an antidepressant such as nefazodone;
an antibiotic such as clarithromycin (Biaxin), dalfopristin/quinupristin (Synercid), erythromycin (E.E.S., EryPed, Ery-Tab, Erythrocin), or telithromycin (Ketek);
an antifungal medication such as clotrimazole (Mycelex Troche) voriconazole (Vfend);
a nitrate heart medication, such as nitroglycerin (Nitrostat, Nitrolingual, Nitro-Dur, Nitro-Bid, and others), isosorbide dinitrate (Dilatrate-SR, Isordil, Sorbitrate), or isosorbide mononitrate (Imdur, ISMO, Monoket);
heart or blood pressure medication such as diltiazem (Cardizem, Dilacor, Tiazac), nicardipine (Cardene), quinidine (Quinaglute, Quinidex, Quin-Release), or verapamil (Calan, Covera, Isoptin, Verelan); or
HIV/AIDS medicine such as amprenavir (Agenerase), atazanavir (Reyataz), delavirdine (Rescriptor), fosamprenavir (Lexiva), indinavir (Crixivan), nelfinavir (Viracept), or saquinavir (Invirase).
This list is not complete and there may be other drugs that can interact with alfuzosin. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.