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Drugs reference index «Accolate»

Accolate
Accolate


Accolate

Generic Name: zafirlukast (za FIR loo cast)Brand Names: Accolate

What is Accolate (zafirlukast)?

Zafirlukast is a leukotriene (loo-koe-TRY-een) inhibitor. Leukotrienes are chemicals your body releases when you breathe in an allergen (such as pollen). These chemicals cause swelling in your lungs and tightening of the muscles around your airways, which can result in asthma symptoms.

Zafirlukast is used to treat and prevent asthma attacks in adults and children as young as 5 years old.

Do not give this medication to a child without a doctor's advice.

Zafirlukast may also be used for other purposes not listed in this medication guide.

What is the most important information I should know about Accolate (zafirlukast)?Do not use zafirlukast to treat an asthma attack that has already begun. It will not work fast enough to reverse your symptoms. Use only a fast-acting inhalation medication to treat an asthma attack. Talk with your doctor if any of your asthma medications do not seem to work as well in treating or preventing asthma attacks. It may take up to several weeks of using this medicine before your symptoms improve. For best results, keep using the medication as directed. Talk with your doctor if your symptoms do not improve after several weeks of treatment.

Call your doctor right away if you feel that this medicine is not working as well as usual, or if it makes your condition worse. If it seems like you need to use more of any of your medications in a 24-hour period, talk with your doctor.

What should I discuss with my healthcare provider before taking Accolate (zafirlukast)?Do not use this medication if you are allergic to zafirlukast.

Before using zafirlukast, tell your doctor if you are allergic to any drugs (especially aspirin), or if you have liver disease. You may not be able to use zafirlukast, or you may need dosage adjustments or special tests during treatment.

The chewable tablet form of this medication may contain up to 0.842 milligrams of phenylalanine. Talk to your doctor before using this form of zafirlukast if you have phenylketonuria (PKU).

FDA pregnancy category B. This medication is not expected to be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment. Zafirlukast can pass into breast milk and may harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

How should I take Accolate (zafirlukast)?

Take this medication exactly as it was prescribed for you. Do not take the medication in larger amounts, or take it for longer than recommended by your doctor. Follow the directions on your prescription label.

Zafirlukast is usually taken once daily in the evening for prevention of asthma or allergy symptoms. Follow your doctor's instructions.

Take zafirlukast on an empty stomach, at least 1 hour before or 2 hours after a meal. Do not use zafirlukast to treat an asthma attack that has already begun. It will not work fast enough to reverse your symptoms. Use only a fast-acting inhalation medication to treat an asthma attack. Talk with your doctor if any of your asthma medications do not seem to work as well in treating or preventing asthma attacks. For best results, keep using zafirlukast as directed. Talk with your doctor if your symptoms do not improve after several weeks of treatment.

Asthma is often treated with a combination of different drugs. To best treat your condition, use all of your medications as directed by your doctor. Be sure to read the medication guide or patient instructions provided with each of your medications. Do not change your doses or medication schedule without advice from your doctor, even if you have no asthma symptoms.

Call your doctor right away if you feel that this medicine is not working as well as usual, or if it makes your condition worse. If it seems like you need to use more of any of your medications in a 24-hour period, talk with your doctor.

Store zafirlukast at room temperature away from moisture and heat.

See also: Accolate dosage in more detail

What happens if I miss a dose?

Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and take the medicine at your next regularly scheduled time. Do not take extra medicine to make up the missed dose.

What happens if I overdose?

Seek emergency medical attention if you think you have used too much of this medicine.

Overdose symptoms may include skin rash and upset stomach.

What should I avoid while taking Accolate (zafirlukast)?

Avoid situations or activities that may trigger an asthma attack.

Accolate (zafirlukast) side effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Call your doctor at once if you have any of these serious side effects:
  • worsening asthma symptoms;

  • mood or behavior changes, anxiety, depression, or thoughts about suicide or hurting yourself;

  • skin rash, bruising, severe tingling, numbness, pain, muscle weakness; or

  • nausea, stomach pain, loss of appetite, itching, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes).

Less serious side effects may include:

  • headache;

  • nausea, vomiting, diarrhea, stomach pain;

  • weakness;

  • dizziness;

  • muscle pain; or

  • fever, sore throat, cold symptoms.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect Accolate (zafirlukast)?

Before using zafirlukast, tell your doctor if you are using any of the following drugs:

  • aspirin;

  • a blood thinner such as warfarin (Coumadin);

  • tolbutamide (Orinase);

  • erythromycin (E.E.S., E-Mycin, Ery-Tab, Erythrocin);

  • theophylline (Elixophyllin, Respbid, Slo-Bid, TheoDur, and others);

  • carbamazepine (Carbatrol, Tegretol); or

  • phenytoin (Dilantin).

This list is not complete and there may be other drugs that can interact with zafirlukast. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.

Where can I get more information?

  • Your pharmacist can provide more information about zafirlukast.
  • Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
  • Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.
Copyright 1996-2006 Cerner Multum, Inc. Version: 5.01. Revision Date: 06/25/2009 10:45:10 AM.
  • Accolate Prescribing Information (FDA)
  • Accolate MedFacts Consumer Leaflet (Wolters Kluwer)
  • Accolate Detailed Consumer Information (PDR)
  • Accolate Advanced Consumer (Micromedex) - Includes Dosage Information
  • Zafirlukast Professional Patient Advice (Wolters Kluwer)

See Also...

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