Alglucosidase Alfa may cause severe allergic reactions, including anaphylactic shock. The reaction may occur while you receive Alglucosidase Alfa or up to 2 hours after. Tell your health care provider immediately if you experience rash; hives; trouble breathing; tightness in the chest; or swelling of the mouth, face, lips, or tongue while receiving Alglucosidase Alfa . Only use Alglucosidase Alfa where appropriate measures to treat a severe allergic reaction are available.
Treating Pompe disease (alfa-glucosidase deficiency).
Alglucosidase Alfa is a glycoprotein. It works by replacing the enzyme alfa-glucosidase in the body.
Contact your doctor or health care provider right away if any of these apply to you.
Some medical conditions may interact with Alglucosidase Alfa . Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:
Some MEDICINES MAY INTERACT with Alglucosidase Alfa . However, no specific interactions with Alglucosidase Alfa are known at this time.
Ask your health care provider if Alglucosidase Alfa may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.
Use Alglucosidase Alfa as directed by your doctor. Check the label on the medicine for exact dosing instructions.
Ask your health care provider any questions you may have about how to use Alglucosidase Alfa .
All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:
Constipation; diarrhea; heartburn; runny nose.Seek medical attention right away if any of these SEVERE side effects occur:
Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); agitation, irritability, or restlessness; blue skin or nails; chest pain or tightness; chills; cold hands or feet; ear pain; excessive or cold sweat; fast, slow, or irregular heartbeat; feeling hot; fever; flushing; headache; increased tear production; nausea; pain, swelling, or redness at the injection site; pale skin; purplish skin discoloration; rapid or difficult breathing; severe headache or dizziness; stomach pain; swelling of the hands, legs, or feet; throat tightness; tremor; unexplained cough; unusual tiredness or weakness; vomiting; wheezing; white patches in the mouth.
This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. You may also report side effects at http://www.fda.gov/medwatch.
Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (http://www.aapcc.org), or emergency room immediately.Proper storage of Alglucosidase Alfa :
Alglucosidase Alfa is usually handled and stored by a health care provider. If you are using Alglucosidase Alfa at home, store Alglucosidase Alfa as directed by your pharmacist or health care provider. Keep Alglucosidase Alfa out of the reach of children and away from pets.
This information is a summary only. It does not contain all information about Alglucosidase Alfa . If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.