Drugs Information Online
Drugs and diseases reference index

Drugs and diseases reference index
Search
EN

Drugs reference index «Flagyl Vaginal»

Flagyl

Generic Name: metronidazole (Vaginal route)

met-roe-NYE-da-zole

Oral routeTabletTablet, Extended ReleaseCapsule

Metronidazole has been shown to be carcinogenic in mice and rats. Unnecessary use of the drug should be avoided .

Metronidazole has been shown to be carcinogenic in mice and rats. Unnecessary use of the drug should be avoided .

Intravenous routeSolution

Metronidazole has been shown to be carcinogenic in mice and rats. Its use, therefore, should be reserved conditions that it is approved for .

Metronidazole has been shown to be carcinogenic in mice and rats. Its use, therefore, should be reserved for conditions that it is approved for .

Commonly used brand name(s):

In the U.S.

  • Metrogel-Vaginal
  • Vandazole

In Canada

  • Flagyl
  • Neo-Metric
  • Nidagel

Available Dosage Forms:

  • Suppository
  • Gel/Jelly
  • Cream

Therapeutic Class: Antibacterial

Chemical Class: Nitroimidazole

Uses For Flagyl

Metronidazole is used to treat certain vaginal infections. It works by killing bacteria. This medicine will not work for vaginal fungus or yeast infections.

Metronidazole is available only with your doctor's prescription.

Before Using Flagyl

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:

In deciding whether to use a medicine, the risks of using the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For vaginal metronidazole, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Studies on these medicines have been done only in adult patients, and there is no specific information comparing use of vaginal metronidazole in children with use in other age groups.

Geriatric

Many medicines have not been studied specifically in older people. Therefore, it may not be known whether they work exactly the same way they do in younger adults or if they cause different side effects or problems in older people. There is no specific information comparing use of metronidazole in the elderly with use in other age groups.

Pregnancy

Pregnancy CategoryExplanation
All TrimestersBAnimal studies have revealed no evidence of harm to the fetus, however, there are no adequate studies in pregnant women OR animal studies have shown an adverse effect, but adequate studies in pregnant women have failed to demonstrate a risk to the fetus.

Breast Feeding

There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

Interactions with Medicines

Using this medicine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.

  • Amprenavir
  • Dihydroergotamine
  • Disulfiram
  • Ergoloid Mesylates
  • Ergonovine
  • Ergotamine
  • Methylergonovine

Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

  • Amiodarone
  • Busulfan
  • Fluorouracil
  • Mycophenolate Mofetil
  • Warfarin

Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

  • Carbamazepine
  • Cholestyramine
  • Cyclosporine
  • Lithium
  • Milk Thistle
  • Tacrolimus

Interactions with Food/Tobacco/Alcohol

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Using this medicine with any of the following is usually not recommended, but may be unavoidable in some cases. If used together, your doctor may change the dose or how often you use this medicine, or give you special instructions about the use of food, alcohol, or tobacco.

  • Ethanol

Other Medical Problems

The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially:

  • Central nervous system (CNS) disease, including epilepsy—Metronidazole may increase the chance of seizures (convulsions) or other side effects
  • Liver disease, severe—Patients with severe liver disease may have an increase in side effects
  • Low white blood cell count (or history of)—Metronidazole may make the condition worse

Proper Use of metronidazole

This section provides information on the proper use of a number of products that contain metronidazole. It may not be specific to Flagyl. Please read with care.

Wash your hands before and after using the medicine. Also, keep the medicine out of your eyes.

If this medicine does get into your eyes, wash them out immediately, but carefully, with large amounts of tap water. If your eyes still burn or are painful, check with your doctor.

Vaginal metronidazole products usually come with patient directions. Read them carefully before using this medicine.

Use vaginal metronidazole exactly as directed by your doctor.

  • To fill the applicator
    • For cream or gel dosage forms:
      • Break the metal seal at the opening of the tube by using the point on the top of the cap.
      • Screw the applicator onto the tube.
      • Squeeze the medicine into the applicator slowly until it is full.
      • Remove the applicator from the tube. Replace the cap on the tube.
    • For vaginal tablet dosage form:
      • Place the vaginal tablet into the applicator. Wet the vaginal tablet with water for a few seconds.
  • To insert vaginal metronidazole using the applicator
    • For all dosage forms:
      • Relax while lying on your back with your knees bent.
      • Hold the full applicator in one hand. Insert it slowly into the vagina. Stop before it becomes uncomfortable.
      • Slowly press the plunger until it stops.
      • Withdraw the applicator. The medicine will be left behind in the vagina.
  • To care for the applicator
    • For all dosage forms:
      • Clean the applicator after use by pulling the plunger out of the applicator and washing both parts completely in warm soapy water.
      • Rinse well.
      • After drying the applicator, replace the plunger.

To help clear up your infection completely, it is very important that you keep using this medicine for the full time of treatment , even if your symptoms begin to clear up after a few days. If you stop using this medicine too soon, your symptoms may return. Do not miss any doses. Also, continue using this medicine even if your menstrual period starts during the time of treatment .

Dosing

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

  • Forvaginal cream dosage form:
    • For bacterial vaginosis or trichomoniasis:
      • Adults and teenagers—One applicatorful (500 milligrams [mg]), inserted into the vagina. Use the medicine one or two times a day for ten or twenty days.
      • Children—Use and dose must be determined by your doctor.
  • Forvaginal gel dosage form:
    • For bacterial vaginosis:
      • Adults and teenagers—One applicatorful (37.5 mg), inserted into the vagina one or two times a day for five days.
      • Children—Use and dose must be determined by your doctor.
  • Forvaginal tablets dosage form:
    • For bacterial vaginosis or trichomoniasis:
      • Adults and teenagers—One 500-mg tablet, inserted high into the vagina. Use the medicine once a day in the evening for ten or twenty days.
      • Children—Use and dose must be determined by your doctor.

Missed Dose

If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.

Storage

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Precautions While Using Flagyl

If your symptoms do not improve within a few days, or if they become worse, check with your doctor.

It is important that you visit your doctor after you have used all your medicine to make sure that the infection is gone.

Drinking alcoholic beverages while using this medicine may cause stomach pain, nausea, vomiting, headache, or flushing or redness of the face. Alcohol-containing medicines (for example, elixirs, cough syrups, tonics) may also cause problems. The chance of these problems occurring may continue for at least a day after you stop using metronidazole. Therefore, you should not drink alcoholic beverages or take other alcohol-containing medicines while you are using this medicine and for at least a day after stopping it.

This medicine may cause some people to become dizzy or lightheaded. Make sure you know how you react to this medicine before you drive, use machines, or do anything else that could be dangerous if you are dizzy or are not alert. If these reactions are especially bothersome, check with your doctor.

Vaginal medicines usually leak out of the vagina during treatment. To keep the medicine from getting on your clothing, wear a minipad or sanitary napkin. Do not use tampons (like those used for menstrual periods) since they may soak up the medicine.

To help clear up your infection completely and to help make sure it does not return, good health habits are also required.

  • Wear cotton panties (or panties or pantyhose with cotton crotches) instead of synthetic (for example, nylon or rayon) panties.
  • Wear only freshly washed panties daily.

Do not have sexual intercourse while you are using this medicine. Having sexual intercourse may reduce the strength of the medicine. This may cause the medicine to not work as well. Also, oils in the cream and vaginal tablets (but not the vaginal gel) may damage latex (rubber) contraceptive devices, such as cervical caps, condoms, or diaphragms, causing them to leak, wear out sooner, or not work properly.

Many vaginal infections (for example, trichomoniasis) are spread by having sexual intercourse. You can give the infection to your sexual partner, and the infection could be given back to you. Your partner may also need to be treated for some infections. Until you are sure that the infection is completely cleared up after your treatment with this medicine, your partner should wear a condom during sexual intercourse . If you have any questions about this, check with your health care professional.

Flagyl Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor as soon as possible if any of the following side effects occur:

More common
  • Itching in the vagina
  • pain during sexual intercourse
  • thick, white vaginal discharge with no odor or with a mild odor
Less common
  • Abdominal or stomach cramping or pain
  • burning or irritation of penis of sexual partner
  • burning on urination or need to urinate more often
  • itching, stinging or redness of the genital area

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Less common
  • Diarrhea
  • dizziness or lightheadedness
  • dryness of mouth
  • headache
  • feeling of a furry tongue
  • loss of appetite
  • metallic taste or other change in taste sensation
  • nausea
  • vomiting

Metronidazole may cause your urine to become dark. This is harmless and will go away when you stop using this medicine.

After you stop using this medicine, it may still produce some side effects that need attention. During this period of time, check with your doctor immediately if you notice the following side effects:

  • Any vaginal or genital irritation or itching
  • pain during sexual intercourse
  • thick, white vaginal discharge not present before treatment, with no odor or with a mild odor

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

The information contained in the Thomson Healthcare (Micromedex) products as delivered by Drugs.com is intended as an educational aid only. It is not intended as medical advice for individual conditions or treatment. It is not a substitute for a medical exam, nor does it replace the need for services provided by medical professionals. Talk to your doctor, nurse or pharmacist before taking any prescription or over the counter drugs (including any herbal medicines or supplements) or following any treatment or regimen. Only your doctor, nurse, or pharmacist can provide you with advice on what is safe and effective for you.

The use of the Thomson Healthcare products is at your sole risk. These products are provided "AS IS" and "as available" for use, without warranties of any kind, either express or implied. Thomson Healthcare and Drugs.com make no representation or warranty as to the accuracy, reliability, timeliness, usefulness or completeness of any of the information contained in the products. Additionally, THOMSON HEALTHCARE MAKES NO REPRESENTATION OR WARRANTIES AS TO THE OPINIONS OR OTHER SERVICE OR DATA YOU MAY ACCESS, DOWNLOAD OR USE AS A RESULT OF USE OF THE THOMSON HEALTHCARE PRODUCTS. ALL IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE OR USE ARE HEREBY EXCLUDED. Thomson Healthcare does not assume any responsibility or risk for your use of the Thomson Healthcare products.

Comment «Flagyl Vaginal»