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Medical Dictionary Definitions A-Z List

Medical Dictionary Definitions A - Z - «M»:

  1. Mutagen Mutagen
    Mutagen: Something capable of causing a gene-change. Among the known mutagens are radiation, certain chemicals and some viruses. ...
  2. Mutagenesis Mutagenesis
    Mutagenesis: The development and production of mutations in the genome....
  3. Mutant Mutant
    Mutant: An individual with a mutant (changed) gene. ...
  4. Mutation Mutation
    Mutation: A permanent change, a structural alteration, in the DNA or RNA. In humans and many other organisms, mutations occur in DNA. However, in retroviruses like HIV, mutations occur in RNA which is the genetic material of retroviruses. In most cases, such changes are neutral and have no effe...
  5. Mutation, acquired Mutation, acquired
    Mutation, acquired: See: Acquired mutation. ...
  6. Mutation, germline Mutation, germline
    Mutation, germline: A heritable change in the DNA that occurred in a germ cell (a cell destined to become an egg or in the sperm) or the zygote (the conceptus) at the single-cell stage. When transmitted to a child, a germline mutation is incorporated in every cell of their body. Germline mutat...
  7. Mutation, hereditary Mutation, hereditary
    Mutation, hereditary: A heritable change in the DNA of a gene or chromosome in a cell destined to become an egg or a sperm or the zygote (the conceptus) at the single-cell stage. When transmitted to a child, an hereditary mutation is incorporated in every cell of their body. Hereditary mutations ...
  8. Mutation, missense Mutation, missense
    Mutation, missense: A genetic change involving the substitution of one base in the DNA for another which results in the substitution of one amino acid in a polypeptide for another. A missense mutation is a "readable" genetic message although its "sense" (its meaning) is changed. This is in contrast...
  9. Mutation, nonsense Mutation, nonsense
    Mutation, nonsense: A mutation (a change) in a base in the DNA that prematurely stops the translation (reading) of messenger RNA (mRNA) resulting in a polypeptide chain that ends prematurely and a protein product that is truncated (abbreviated) and incomplete and usually nonfunctional. The nonsen...
  10. Mutation, null Mutation, null
    Mutation, null: A mutation (a change) in a gene that leads to its not being transcribed into RNA and/or translated into a functional protein product. For example, a null mutation in a gene that usually encodes a specific enzyme leads to the production of a nonfunctional enzyme or no enzyme at all....
  11. Mutation, point Mutation, point
    Mutation, point: A single nucleotide base change in the DNA. A point mutation may consist of the loss of a nucleotide, the insertion of an additional nucleotide, or the substitution of one nucleotide for another. The first point mutation discovered in humans involved the substitution of one nucleo...
  12. Mutation, private Mutation, private
    Mutation, private: A rare mutation found usually only in a single family or a small population. (It is like a privately printed book.)...
  13. Mutation, somatic Mutation, somatic
    Mutation, somatic: See: Somatic mutation. ...
  14. Mute Mute
    Mute: A mute is a person who does not speak, either from an inability to speak or an unwillingness to speak. The term "mute" is specifically applied to a person who, due to profound congenital (or early) deafness, is unable to use articulate language and so is deaf-mute. A mute in speech is a le...
  15. Mutilating keratoderma Mutilating keratoderma
    Mutilating keratoderma: See: Vohwinkel syndrome....