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Definition of «Acromegaly»


Acromegaly: Condition due to the production of too much growth hormone by the pituitary gland after the end of adolescence.

When there is secretion of too much growth hormone before the end of adolescence, gigantism results. People with pituitary gigantism can truly be giants; they can sometimes end up over 7 or 8 feet in height.

When too much growth hormone is secreted after adolescence, there cannot be an increase in height but acromegaly ensues. The cardinal manifestations of acromegaly include thickening of the skin, soft tissues, and bones of the hands and feet. These effects are insidious and very slowly progressive. Ultimately they cause considerable disability (aside from the need for larger rings, gloves, and shoes) including hoarseness, sleep apnea, joint pain, cardiovascular disease, hypertension, insulin resistance, visual impairment and severe headaches.

Excessive growth hormone secretion may be caused by an adenoma of the pituitary (a tumor of the pituitary) or by other causes. Treatment is usually possible via medication or surgery. Inadequate treatment of pituitary gigantism or acromegaly is associated with increases in deaths from cardiovascular causes, cancer, and other causes.

For More Information «Acromegaly»

  • acromegaly.org - What is Acromegaly?

    Acromegaly is a hormonal disorder that most commonly occurs in middle-aged men and women. The prevalence of acromegaly is approximately 60 cases per million population ...

  • Acromegaly - PubMed Health - National Center for ...

    Acromegaly is a chronic metabolic disorder in which there is too much growth hormone and the body tissues gradually enlarge.

  • Acromegaly - MayoClinic.com - Mayo Clinic

    Acromegaly — Comprehensive overview covers symptoms, causes, treatment of this hormonal disorder.

  • Acromegaly

    Acromegaly is a serious condition that occurs when the body produces too much of the hormones that control growth. The hormone most often affected is called growth ...

  • Acromegaly

    Acromegaly is a rare, insidious, and potentially life-threatening condition for which there is good, albeit incomplete, treatment that can add years of high ...

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