Adrenoleukodystrophy: A rare genetic (inherited) disorder characterized by the breakdown or loss of the myelin sheath surrounding nerve cells in the brain and progressive dysfunction of the adrenal gland. Adrenoleukodystrophy (ALD) is one of a group of genetic disorders called the leukodystrophies that cause damage to the myelin sheath of the nerve fibers in the brain. The myelin sheath is a fatty covering which acts as an electrical insulator.
There are several forms of ALD:
The treatment for all forms of ALD is symptomatic and supportive. Physical therapy, psychological support, and special education may be useful for some individuals.
The prognosis for patients with ALD is generally poor due to progressive neurological deterioration. Death usually occurs within 1 to 10 years after the onset of symptoms.
n. ( Abbr. ALD ) A genetic disorder affecting boys, characterized by adrenocortical insufficiency , hyperpigmentation , and leukodystrophy
Information sheet on Adrenoleukodystrophy compiled by NINDS. ... What is Adrenoleukodystrophy? Adrenoleukodystrophy (ALD) is one of a group of genetic disorders ...
Adrenoleukodystrophy describes several closely related inherited disorders that disrupt the breakdown of certain fats (very-long-chain fatty acids).
The Adrenoleukodystrophy Foundation, a non-profit organization created to educate about ALD, AMN and Addison's Disease. Our motto: Care Today for a Cure Tomorrow.
Adrenoleukodystrophy describes several closely related inherited disorders that disrupt the breakdown (metabolism) of certain fats (very-long-chain fatty ...