Aggressive angiomyxoma: A slow-growing tumor of stromal cells which occurs primarily in the genital and pelvic regions. This tumor is much more common in women. It can range from relatively small tumors to football-size masses in the pelvis. The histologic appearance of the tumor under the microscope is rather distinctive.
Treatment consists of surgical excision (removal). Unfortunately, there is a relatively high rate of recurrence because the exact extent of the tumor is difficult for the surgeon to determine. These tumors appear not to have the ability to metastasize (spread to distant organs).
Fishman-A; Aggressive angiomyxoma of the pelvis and perineum. A case report. J-Reprod-Med. 1995 Sep; 40(9): 665-9.
Fetsch JF; Aggressive angiomyxoma: a clinicopathologic study of 29 female patients. Cancer Vol. 78 no. 1 pp. 79-90.
PATHOGENESIS: CHARACTERIZATION: CHROMOSOMAL ABNORMALITIES : Chromosomal translocation t(8;12) induces aberrant HMGIC expression in aggressive angiomyxoma of the vulva.
Definition. Infiltrative, hypocellular, bland myxoid lesion of perineum and pelvis ; Diagnostic Criteria . Virtually restricted to deep soft tissue of perineum, external ...
Aggressive angiomyxoma is a rare locally aggressive mesenchymal tumour which was first described by Steeper TA and Rosai J in 1983. The tumour infiltrates locally ...
Soft Tissue Tumors: Aggressive angiomyxoma, Authors: Francesca Micci, Petter Brandal. Published in: Atlas Genet Cytogenet Oncol Haematol.
Alex Mathieson, MD, * Soorna Chandrakanth, MD, â€ George Yousef, MD, â€ Patricia Wadden, MD, â€ Eric Sala, MD, â€¡ and Debrah Wirtzfeld, MD *