Angiostatin: Angiostatin is a piece (a fragment) of a protein, plasminogen, used normally in blood clotting. This fragment is normally secreted by tumors. It appears to halt the process of developing new blood vessels (angiogenesis) which is necessary to tumor development. Angiostatin may, it is hoped, represent a prototype for a new class of agents with which to treat cancer.
Library > Literature & Language > Dictionary ( ăn ' jÄ“-Å-stăt ' n ) n. A naturally occurring protein that is a specific inhibitor of endothelial proliferation and ...
Haematologic Technologies, Inc is a primary manufacturer of high-quality coagulation proteins and research reagents including human angiostatin.
Injections of angiostatin inhibit the metastasis of certain (mouse) primary tumors. Injections of endostatin (made by recombinant DNA technology) cause the primary tumor ...
Cytokines & Cells Online Pathfinder Encyclopedia ... Angiostatin. Angiostatin was observed initially as an angiogenesis inhibitor in serum and urine of mice bearing a Lewis lung ...
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