Annexin A1: One of the annexins, a family of proteins that share the property of binding calcium and phospholipids. The gene for annexin A1 (ANXA1) is upregulated in hairy cell leukemia. ANXA1 protein expression is specific to hairy cell leukemia. Detection of ANXA1 (by immunocytochemical means) reportedly provides a simple, highly sensitive and specific assay for the diagnosis of hairy cell leukemia.
1 Biochemical Pharmacology, William Harvey Research Institute, Barts and the London School of Medicine and Dentistry, Charterhouse Square, London, UK
MP Protein ID: A000277: Protein Name: Annexin A1: Protein Synonyms: Annexin 1; Annexin A 1; Annexin A1; ANX A1; ANX1; Anxa1; Calpactin-2; Lipocortin I; Lipocortin-1; Liporcortin 1 ...
Annexin (ANXA1) is strongly expressed on the cell membrane and occasionally in the cytoplasm of tumor cells in 97% of samples from patients with hairy cell leukemia.
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The William Harvey Research Institute, Barts and The London School of Medicine, Queen Mary University of London, Charterhouse Square, London, UK