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Anthracycline: A member of a family of chemotherapy drugs that are also antibiotics. The anthracyclines act to prevent cell division by disrupting the structure of the DNA and terminate its function. They do so in two ways: (1) they intercalate into the base pairs in the DNA minor grooves; and (2) they cause free radical damage of the ribose in the DNA. The anthracyclines are frequently used in leukemia therapy. The anthracyclines include daunorubicin (Cerubidine), doxorubicin (Adriamycin, Rubex), epirubicin (Ellence, Pharmorubicin), and idarubicin (Idamycin).
A class of antibiotics isolated from cultures of Streptomyces peucetius ; it includes the antineoplastic agents daunomycin and doxorubicin. See also anthracycline ...
Anthracycline: A member of a family of chemotherapy drugs that are also antibiotics. The anthracyclines act to prevent cell division by disrupting the structure of the DNA ...
Chemotherapy with an anthracycline drug such as doxorubicin or epirubicin extends survival for women with HER2-positive, but not HER2-negative, breast cancer, according ...
anthracycline /an·thra·cy·cline/ (-si´klēn) a class of antineoplastic antibiotics produced by Streptomyces peucetius and S. coeruleorubidus, including daunomycin ...
Anthracycline. Lifestyle, fitness & health information about Anthracycline. Anthracyclines in Breast Cancer, What Are the Treatments for Acute Promyelocytic Leukemia ...