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Definition of «Antisense»

AntisenseAntisense

Antisense: In molecular biology, the strand complementary to a coding sequence of a nucleic acid.

Antisense DNA is the non-coding strand complementary to the coding strand in double-stranded DNA. The antisense strand serves as the template for messenger RNA (mRNA) synthesis.

Antisense RNA is the non-coding strand complementary to a coding sequence of mRNA, a molecule involved in translating genetic instructions into proteins. Antisense RNA hybridizes with and inactivates mRNA.

Antisense drugs are based on the fact that antisense RNA hybridizes with and inactivates mRNA. These drugs are short sequences of RNA that attach to mRNA and stop a particular gene from producing the protein for which it holds the recipe. Antisense drugs are being developed to treat lung cancer, diabetes and diseases such as arthritis and asthma with a major inflammatory component.

For More Information «Antisense»

  • antisense: Definition from Answers.com

    adj. Of or relating to a nucleotide sequence that is complementary to a sequence of messenger RNA. When antisense DNA or RNA is added to a cell, it binds to a ...

  • Antisense RNA

    Antisense RNA. Messenger RNA (mRNA) is single-stranded. Its sequence of nucleotides is called "sense" because it results in a gene product (protein).

  • Antisense Network

    Get information of Antisense, antisense therapy, DNA, RNA and Antisense Technology. Antisense means a molecule which does suppresses transcription with a complementary ...

  • Antisense, RNAi, and Gene Silencing Strategies for Therapy ...

    Antisense oligonucleotides can regulate gene expression in living cells. As such, they regulate cell function and division, and can modulate cellular responses to ...

  • Antisense | Define Antisense at Dictionary.com

    adjective of or pertaining to a gene that is derived from RNA or complementary DNA, is inserted in reverse orientation into a strand of DNA, and is used in genetic ...

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