Aspirin resistance: 1. The inability of aspirin to protect a person from cardiovascular events such as heart attacks and strokes. This has been called clinical aspirin resistance.
2. The inability of aspirin to produce an anticipated effect on one or more tests of platelet function. This has been called biochemical aspirin resistance, although the tests are not all truly biochemical in nature.
See: Biochemical aspirin resistance; Clinical aspirin resistance.
Abstract. Aspirin resistance is the inability of aspirin to reduce platelet production of thromboxane A2 and thereby platelet activation and aggregation.
Measurement of Aspirin Resistance: About 26 million Americans take aspirin daily to prevent heart attacks, but how many are actually receiving a benefit?
Cyclooxygenase-1 [COX-1, prostaglandin synthase] catalyses the transformation of arachidonic acid to the unstable intermediate prostaglandin PGH2. Subsequently ...
May be a cause of recurrent ischaemic vascular events in patients taking aspirin. Aspirin reduces the odds of serious atherothrombotic vascular events and death in a broad ...
Introduction: Dr. Powers Peterson focuses on testing for possible aspirin resistance in her highlights of the 2005 American Society for Clinical Pathology annual meeting.