Bowen's disease: An early stage of skin cancer.
Bowen's disease is medically the same as "squamous cell carcinoma in situ." Squamous cell carcinoma is a tumor that develops from the squamous cells which are flat, scale-like cells in the outer layer of the skin (the epithelium). The term "in situ" (borrowed from the Romans) means "in the natural or normal place" and, in the case of cancer, it says that the tumor cells are still confined to the site where they originated and they have neither invaded neighboring tissues nor metastasized afar.
The hallmark of Bowen's disease is a persistent, progressive, slightly raised, red, scaly or crusted plaque. Bowen's disease may occur anywhere on the skin surface (or on mucosal surfaces such as in the mouth).
Under the microscope, atypical squamous cells are seen to have proliferated through the whole thickness of the epidermis (the outer layer of the skin) but to have gone no farther.
The cause of Bowen's disease classically was prolonged exposure to arsenic. Today, Bowen's disease occurs most often in the sun-exposed areas of the skin in "older" white males.
Treatment options include freezing with liquid nitrogen, cauterization (burning), surgical removal, and chemosurgery.
Bowen's disease is named after the American dermatologist John Templeton Bowen's (1857-1941).
First described by the American dermatologist John T. ... Instant Lookup Access over 10,000 topics by title ...or, search within full reference content
Bowen's disease, which is also called 'squamous cell carcinoma in situ', is a form of skin cancer. The term
Library > Science > Sci-Tech Dictionary ( â€²bÅÂ·É™nz diâ€²zÄ“z ) ( medicine ) Intraepithelial squamous-cell carcinoma of the skin, forming distinctive plaques. A ...
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Bowen's disease information including symptoms, diagnosis, misdiagnosis, treatment, causes, patient stories, videos, forums, prevention, and prognosis.