Castleman's disease: A disorder of lymphoid tissue (lymphadenopathy) with massive overgrowth (hyperplasia) of lymph nodes ("swollen glands"), most commonly affecting the nodes between the lungs (in the mediastinum).
There are two quite different forms of Castleman's disease. One form, found in 90% cases, is a localized kind of lymphadenopathy. It usually causes no symptoms, follows an indolent (lazy) course and can be cured simply by excision (surgical removal).
The far more ominous form of Castleman's disease, encountered in 10% of cases, is a multicentric lymphadenopathy with progressive systemic signs and symptoms such as fever and anemia. This rapidly progressive multicentric type of Castleman's disease is associated with infection by human herpesvirus 8 (HHV-8).
The disease was first described by B. Castleman's and colleagues in 1956.
Castleman disease â€” Comprehensive overview covers symptoms, causes, treatment of this lymphatic disorder.
International Castleman's Disease Organization ... ICDO hosted a one-day summit on Wednesday, December 2, 2009 in New Orleans.
Article describes Castleman disease, its types, its symptoms, diagnosis, and treatment.
International Castleman's Disease Organization ... Our Mission Statement The International Castlemans Disease Organization is a non-profit institution committed to promoting ...
Castleman disease (CD) is a disease of lymph nodes and related tissues.