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Catechol-O-methyltransferase: COMT. An enzyme that catalyzes the degradation of catecholamines, including the neurotransmitters dopamine, epinephrine, and norepinephrine. COMT is also important in the metabolism of catechol drugs used in the treatment of hypertension, asthma, and Parkinson disease. A genetic polymorphism (a common normal variant) in COMT contributes to the responses to pain and stress.
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Official Symbol COMT provided by HGNC Official Full Name catechol-O-methyltransferase provided by HGNC
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Catechol O-methyltransferase information including symptoms, causes, diseases, symptoms, treatments, and other medical and health issues.
The COMT gene provides instructions for making an enzyme called catechol-O-methyltransferase. Two versions of this enzyme are made from the gene.