Drugs Information Online
Drugs and diseases reference index

Drugs and diseases reference index

Definition of «Cell, stem»

Cell, stemCell, stemCell, stemCell, stem

Cell, stem: An ancestral cell, the most primitive type of cell.

Stem cells are relatively unspecialized (undifferentiated) cells that are characteristically of the same family type (lineage). They retain the ability to divide throughout life and give rise to cells that can become highly specialized and take the place of cells that die or are lost.

Stem cells thus contribute to the body's ability to renew and repair its tissues. Unlike mature cells, which are permanently committed to their fate, stem cells can both renew themselves as well as create new cells of whatever tissue they belong to (and other tissues).

Bone marrow stem cells, for example, are the most primitive cells in the marrow. From them all the various types of blood cells are descended. Bone marrow stem-cell transfusions (or transplants) were originally given to replace various types of blood cells.

Stem cells from bone marrow can also, quite remarkably, give rise to non-marrow cells. In a 1999 report in the journal Nature, scientists from Boston led by Dr. Louis M. Kunkel reported that they gave bone marrow transplants from normal mice to dystrophic mice. Some 12 weeks later about 10% of the muscle fibers in the diseased animals were making the correct form of dystrophin, the protein that is defective in Duchenne muscular dystrophy. This work suggests that bone marrow stem cells may offer new ways of treating muscular dystrophy (and other non-blood diseases).

For More Information «Cell, stem»

  • Stem Cell Basics [Stem Cell Information]

    Primer providing basic information about stem cells.

  • Sperm from mice stem cells offers infertility ...

    Read 'Sperm from mice stem cells offers infertility hope' on Yahoo! News. A team of scientists has reported producing viable sperm using the stem cells of mice in an ...

  • Cell Stem Cell

    X Volume 9, Issue 2. On the cover: In this issue, Hoch et al. (pp. 131–143) show that defects in endothelial differentiation by cardiac progenitor cells that are induced ...

  • Cell Stem Cell

    X Volume 9, Issue 1. On the Cover: In this issue, Hong et al (pp. 24–36) use cell surface markers to subdivide hESC cultures into cell populations with distinct ...

  • Report: Rick Perry had experimental stem cell therapy

    Texas Gov. Rick Perry got an injection of his own stem cells when he had back surgery last month -- an experimental therapy that's not approved by the Food ...

Comment «Cell, stem»