Cleidocranial dysostosis: A genetic (inherited) disorder of bone development characterized by:
The disorder is transmitted in an autosomal dominant manner. A parent with the condition has a 50:50 chance that each of their children will have the condition. Boys and girls stand an equal chance of being affected. The gene for the condition has been found on chromosome 6 (specifically, in band p21). The gene is for the transcription factor CBFA1 (core-binding factor alpha subunit 1). Mutations of CBFA1 cause this disorder.
A possible example of this disorder has been found in the skull of a Neanderthal man. (The patient could not be interviewed as to family history).
Cleidocranial dysostosis is a disorder involving the abnormal development of bones in the skull and collar (clavicle) area. The condition is passed down ...
Library > Science > Sci-Tech Dictionary ( ¦klī·dŦkrÄn·ē·əl ¦dis·ä′stÅ·sÉ™s ) ( medicine ) A congenital defect in which there is deficient formation ...
Cleidocranial dysostosis is a disorder involving the abnormal development of bones in the skull and collar (clavicle) area. The condition is passed down ...
What is Cleidocranial Dysplasia? Cleidocranial Dysplasia (cleido = collar bone, + cranial = head, + dysplasia = abnormal forming) , also known as Cleidocranial Dysostosis ...
Cleidocranial dysostosis - Overview, Cleidocranial dysostosis is disorder involving the...