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Definition of «Clinical research trials»

Clinical research trials: Trials to evaluate the effectiveness and safety of medications or medical devices by monitoring their effects on large groups of people.

Clinical research trials may be conducted by government health agencies such as NIH, researchers affiliated with a hospital or university medical program, independent researchers, or private industry.

Usually volunteers are recruited, although in some cases research subjects may be paid. Subjects are generally divided into two or more groups, including a control group that does not receive the experimental treatment, receives a placebo (inactive substance) instead, or receives a tried-and-true therapy for comparison purposes.

Typically, government agencies approve or disapprove new treatments based on clinical trial results. While important and highly effective in preventing obviously harmful treatments from coming to market, clinical research trials are not always perfect in discovering all side effects, particularly effects associated with long-term use and interactions between experimental drugs and other medications.

For some patients, clinical research trials represent an avenue for receiving promising new therapies that would not otherwise be available. Patients with difficult to treat or currently "incurable" diseases, such as AIDS or certain types of cancer, may want to pursue participation in clinical research trials if standard therapies are not effective. Clinical research trials are sometimes lifesaving.

For More Information «Clinical research trials»

  • Home - ClinicalTrials.gov

    Searchable database which provides patients, family members and the public with information about current ongoing clinical research studies. From the U.S. National ...

  • Clinical Research Trials

    Clinical research trials are actively recruiting volunteers in major cities across the country. These studies are being done in many countries including Europe and the US.

  • The Global Source for Clinical Trials Information | CenterWatch

    CenterWatch provides a variety of clinical research products and services: including trial listings and results, drug approvals, study grants, news and analysis, career ...

  • Clinical Research & Clinical Trials

    Clinical research is research that either directly involves a particular person or group of people or uses materials from humans, such as their behavior or ...

  • Oncology Clinical Trials in Emerging Regions

    Increasing the number and quality of clinical research trials in emerging regions should yield important new data about the epidemiology and biology of cancers that has ...

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