Clinical trials: Trials to evaluate the effectiveness and safety of medications or medical devices by monitoring their effects on large groups of people.
Clinical research trials may be conducted by government health agencies such as NIH, researchers affiliated with a hospital or university medical program, independent researchers, or private industry.
Usually volunteers are recruited, although in some cases research subjects may be paid. Subjects are generally divided into two or more groups, including a control group that does not receive the experimental treatment, receives a placebo (inactive substance) instead, or receives a tried-and-true therapy for comparison purposes.
Typically, government agencies approve or disapprove new treatments based on clinical trial results. While important and highly effective in preventing obviously harmful treatments from coming to market, clinical research trials are not always perfect in discovering all side effects, particularly effects associated with long-term use and interactions between experimental drugs and other medications.
For some patients, clinical research trials represent an avenue for receiving promising new therapies that would not otherwise be available. Patients with difficult to treat or currently "incurable" diseases, such as AIDS or certain types of cancer, may want to pursue participation in clinical research trials if standard therapies are not effective. Clinical research trials are sometimes lifesaving.
There are four possible outcomes from a clinical trial:
ClinicalTrials.gov is a registry and results database of federally and privately supported clinical trials conducted in the United States and ...
ClinicalTrials.com is a comprehensive resource for trusted information about medical research studies, also called clinical trials. Whether youâ€™re interested in ...
We Bring Clinical Trials to YOU! Clinical trials determine if new research treatments effectively treat or even cure medical conditions. Join us to be notified when new ...
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Information from the National Cancer Institute on how to find cancer clinical trials, what clinical trials are, recent research, resources for researchers.