Complete androgen insensitivity syndrome: A genetic disorder that makes XY fetuses insensitive (unresponsive) to androgens (male hormones). Instead, they are born looking externally like normal girls. Internally there is a short blind-pouch vagina and no uterus, Fallopian tubes, or ovaries. There are testes in the abdomen or the inguinal canal. The complete androgen insensitivity syndrome is usually detected at puberty when a girl should but does not begin to menstrate. The gene for the syndrome is on the X chromosome and codes for the androgen receptor (also called the dihydrotestosterone receptor). There are also partial androgen insensitivity syndrome.
People with complete androgen insensitivity syndrome also have sparse or absent hair in the pubic area and under the arms. The partial and mild forms of ...
Most mutations to the testosterone-binding region, and some other types of mutations, cause complete androgen insensitivity syndrome (CAIS). In this form of the syndrome ...
Complete Androgen Insensitivity Syndrome is a new information booklet, published by Dr Garry Warne, Director of Endocrinology and Diabetes at RCH.
COMPLETE ANDROGEN INSENSITIVITY SYNDROME (CAIS) CAIS is a rare inherited condition in which babies with male sex chromosomes develop as girls because their bodies are ...
Amy B. Wisniewski, Claude J. Migeon, Heino F. L. Meyer-Bahlburg, John P. Gearhart