Cystine kidney stones: Cystine kidney stones are due to cystinuria, an inherited (genetic) disorder of the transport of an amino acid (a building block of protein) called cystine that results in an excess of cystine in the urine (cystinuria) and the formation of cystine stones.
Cystinuria is the most common defect in the transport of an amino acid. Although cystine is not the only overly excreted amino acid in cystinuria, it is the least soluble of all naturally occurring amino acids. Cystine tends to precipitate out of urine and form stones (calculi) in the urinary tract.
Small stones are passed in the urine. However, big stones remain in the kidney (nephrolithiasis) impairing the outflow of urine while medium-size stones make their way from the kidney into the ureter and lodge there further blocking the flow of urine (urinary obstruction).
Obstruction of the urinary tract puts pressure back up on the ureter and kidney. causing the ureter to widen (dilate) and the kidney to be compressed. Obstruction also causes the urine to be stagnant (not moving), an open invitation to repeated urinary tract infection. The pressure on the kidneys and the urinary infections results in damage to the kidneys. The damage can progress to renal insufficiency and end-stage kidney disease, requiring renal dialysis or a transplant.
The stone are responsible for all the signs and symptoms of cystinuria, including:
For a fuller understanding of cystinuria, including the diagnosis, the different modes of treatment, the genetics of cystinuria and the prognosis for persons with this disease, please see the Cystinuria article.
Cystine kidney stones: Cystine kidney stones are due to cystinuria, an inherited (genetic) disorder of the transport of an amino acid (a building block of protein) called ...
... can form in the urinary tract and "ring calcifications," I.e., calcium encrustations can form around foreign bodies including catheters, stents and cystine kidney stones.
Cystine kidney stones are the rarest type of kidney stone and are more likely to form in people who have cystinuria, a hereditary metabolic disorder.
Cystinuria is a rare, autosomal recessive cause of kidney stones. Cystine stones are found in 1 to 2 percent of stone formers, although they represent a higher percentage ...
Cystine stones are the hardest of all kidney stones in composition, so this means they are the hardest to dissolve and break up. But consider the source~like we mentioned ...