Defensin: A family of potent antibiotics made within the body by neutrophils (a type of white blood cell) and macrophages (cells that can engulf foreign particles). The defensins play important roles against invading microbes. They act against bacteria, fungi and viruses by binding to their membranes and increasing membrane permeability. On a chemical level, the defensins are small peptides unusually rich in the amino acid cysteine (Cys).The human defensins are classified into the alpha-defensins and beta-defensins on the basis of their sequence homology and their Cys residues.
From the Latin defendo, to repel. Defensin is also called human neutrophil peptide (HNP).
Defensin: A family of potent antibiotics made within the body by neutrophils (a type of white blood cell) and macrophages (cells that can engulf foreign particles).
defensin /deÂ·fenÂ·sin/ (de-fenÂ´sin) any of a group of small antimicrobial cationic peptides occurring in neutrophils and macrophages. defensin
deÂ·fenÂ·sin definition Pronunciation: /di-Ëˆfen(t)-sÉ™n/ Function: n : any of a class of peptides that are found in neutrophils and have antimicrobial and cytotoxic ...
Defensins are small (15-20 residue) cysteine-rich cationic proteins found in both vertebrates and invertebrates. They are active against bacteria, fungi and enveloped ...
Defensins Knowledgebase - a collaboration between Bioinformatics Institute and the Singapore Eye Research Insitute