Disease, Pick: A form of dementia characterized by a slowly progressive deterioration of social skills and changes in personality leading to impairment of intellect, memory, and language.

Dementia can be defined as a loss of intellectual abilities such as memory capacity, severe enough to interfere with social or occupational functioning. The criteria for the diagnosis of dementia include impairment of attention, orientation, memory, judgment, language, motor and spatial skills, and function. By definition, dementia is not due to major depression or schizophrenia.