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DNA repair gene: A gene engaged in DNA repair. When a DNA repair gene is impaired, mutations pile up throughout the DNA.
The DNA in genes is constantly mutating and being repaired. This repair process is controlled by special genes. A mutation in a DNA repair gene can cripple the repair process and cause a cascade of unrepaired mutations in the genome that lead to cancer.
Looping the intervening DNA brings the duplicates together and allowing repair by homologous recombination. Gene Conversion. If the sequence used as a template for ...
Human DNA Repair Genes This is the supplement to the review by Wood RD, Mitchell M, & Lindahl T published in Mutation Research, 2005. It is an update of the ...
DNA repair genes play an important role in preserving the integrity of your DNA and preventing the onset of illness and disease.
DNA repair gene: A gene engaged in DNA repair. When a DNA repair gene is impaired, mutations pile up throughout the DNA. The DNA in genes is constantly mutating and ...
In cells with one normal and one mutant allele of a DNA mismatch repair gene, DNA repair is minimally impaired, if at all. However, inactivation of the remaining allele ...